Miguel André Q, Smith Crystal L, Rodin Nicole M, Johnson Ron K, McDonell Michael G, McPherson Sterling M
Elson S Floyd College of Medicine, Washington State University, Spokane, WA, United States.
Analytics and PsychoPharmacology Laboratory, Spokane, WA, United States.
Drug Alcohol Depend Rep. 2023 Feb 1;6:100140. doi: 10.1016/j.dadr.2023.100140. eCollection 2023 Mar.
Alcohol Use Disorder (AUD) is the most prevalent substance use disorder in the United States and is directly related to 5% of all annually reported deaths worldwide. Contingency Management (CM) is among the most effective interventions for AUD, with recent technological advancements allowing CM to be provided remotely. To evaluate the feasibility and acceptability of a mobile Automated Reinforcement Management System (ARMS) designed to provide CM for AUD remotely. Twelve participants with mild or moderate AUD were exposed to ARMS in a A-B-A within-subject experimental design where they were required to submit three breathalyzer samples per day. During the B phase participants could earned rewards with monetary value for submitting negative samples. Feasibility was determined by the proportion of samples submitted and retention in the study and acceptability was based on participants self-reported experience. The mean number of samples submitted per day was 2.02 out of 3. The proportion of samples submitted in each phase was 81.5%, 69.4% and 49.4%, respectively. Participants were retained for a mean of 7.5 (SD=1.1) out of 8 weeks with 10 participants (83.3%) completing the study. All participants found the app easy to use and stated it helped them reduce their alcohol use. Eleven (91.7%) would recommend the app as an adjunct to AUD treatment. Preliminary indicators of efficacy are also presented. ARMS has shown to be feasible and well accepted. If shown effective, ARMS can serve as an adjunctive treatment for AUD.
酒精使用障碍（AUD）是美国最普遍的物质使用障碍，在全球每年报告的所有死亡病例中，有5%与之直接相关。应急管理（CM）是治疗AUD最有效的干预措施之一，最近的技术进步使CM能够远程提供。为了评估一种旨在为AUD远程提供CM的移动自动强化管理系统（ARMS）的可行性和可接受性。12名轻度或中度AUD患者在A-B-A受试者内实验设计中接触ARMS，要求他们每天提交三份呼气酒精含量测定仪样本。在B阶段，参与者提交阴性样本可获得具有货币价值的奖励。可行性通过提交样本的比例和研究中的留存率来确定，可接受性基于参与者自我报告的体验。每天提交的样本平均数为3份中的2.02份。各阶段提交样本的比例分别为81.5%、69.4%和49.4%。参与者在8周内平均留存7.5周（标准差=1.1），10名参与者（83.3%）完成了研究。所有参与者都觉得该应用程序易于使用，并表示它帮助他们减少了酒精使用。11名（91.7%）参与者会推荐该应用程序作为AUD治疗的辅助手段。还呈现了疗效的初步指标。ARMS已被证明是可行的且广受接受。如果证明有效，ARMS可作为AUD的辅助治疗手段。
