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病例报告:诊断、治疗及演变过程:一例巨大且浸润性心脏肿物合并完全性房室传导阻滞。

Case report: Diagnosis, management and evolution of a bulky and invasive cardiac mass complicated by complete atrioventricular block.

作者信息

Bohbot Yohann, Garot Jérôme, Danjon Isabelle, Thébert Dominique, Nahory Louis, Gros Philippe, Salerno Fiorella, Garot Philippe

机构信息

Institut Cardiovasculaire Paris Sud, Hôpital Privé Jacques CARTIER, Ramsay Santé, Massy, France.

Intensive Care Unit Department, Hôpital Privé Jacques CARTIER, Ramsay Santé, Massy, France.

出版信息

Front Cardiovasc Med. 2023 Mar 14;10:1135233. doi: 10.3389/fcvm.2023.1135233. eCollection 2023.

Abstract

INTRODUCTION

Cardiac lymphoma is a rare but serious disease that is usually located in the right heart. The symptoms (dyspnea, respiratory distress, fatigue, syncope…) are not specific and depend on the mass location. Cardiac magnetic resonance has a crucial role in the diagnostic strategy but biopsy is mandatory to confirm the diagnosis.

CASE PRESENTATION

We report the case of a 63-yeart old man who presented with severe dyspnea and complete atrioventricular block (AVB). A bulky and invasive mass was found in the left atrium extending to the right atrium through the interatrial septum. A cardiac lymphoma was suspected by cardiac magnetic resonance (CMR) imaging and confirmed by transvenous biopsy. The patient was treated with urgent chemotherapy (R-CHOP) and pacemaker implantation. After 4 cycles of R-CHOP the patient was in complete remission with total disappearance of the mass and return of a spontaneous sinus rhythm.

CONCLUSION

lymphoma is a therapeutic emergency as appropriate treatment can lead to complete remission even when the mass is extensive and invasive. Complete AVB is a potentially reversible complication of cardiac lymphoma, and the decision to implant a pacemaker must be carefully weighed.

摘要

引言

心脏淋巴瘤是一种罕见但严重的疾病,通常位于右心。其症状(呼吸困难、呼吸窘迫、疲劳、晕厥等)不具有特异性,取决于肿块的位置。心脏磁共振在诊断策略中起着关键作用,但活检是确诊的必要手段。

病例报告

我们报告一例63岁男性患者,表现为严重呼吸困难和完全性房室传导阻滞(AVB)。在左心房发现一个巨大的浸润性肿块,通过房间隔延伸至右心房。心脏磁共振(CMR)成像怀疑为心脏淋巴瘤,并经静脉活检确诊。患者接受了紧急化疗(R-CHOP)和起搏器植入。经过4个周期的R-CHOP治疗后,患者完全缓解,肿块完全消失,恢复自发窦性心律。

结论

淋巴瘤是一种治疗急症,因为即使肿块广泛且浸润,适当治疗也可导致完全缓解。完全性AVB是心脏淋巴瘤的一种潜在可逆并发症,植入起搏器的决定必须谨慎权衡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53ef/10043437/ada0d450df7f/fcvm-10-1135233-g001.jpg

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