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发热病例分离株的抗菌耐药性和生物膜形成:来自印度奥里萨邦农村队列的研究结果。

Antimicrobial Resistance and Biofilm Formation of Isolates from Febrile Cases: Findings from a Rural Cohort of Odisha, India.

机构信息

ICMR-Regional Medical Research Centre, Chandrasekharpur, Bhubaneswar, India.

出版信息

Pol J Microbiol. 2023 Jun 14;72(2):209-214. doi: 10.33073/pjm-2023-005. eCollection 2023 Jun 1.

DOI:10.33073/pjm-2023-005
PMID:37013928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10266288/
Abstract

This study investigated the major pathogens in fever patients' blood in a rural cohort and characterized its virulence. A total of 718 blood samples received from IPD/OPD (inpatient department/outpatient department) patients with H/O (history of) fever were cultured, and 73 out of 83 culture-positive samples were identified as . The isolates showed higher resistance to penicillin, most being multidrug resistant. They formed biofilm , and 27.4% of the isolates were strong biofilm producers. They were sensitive towards linezolid, gentamicin, and tetracycline. The findings emphasize the necessity of preventing and managing staphylococcal infection and regular antimicrobial surveillance in rural areas.

摘要

本研究调查了农村队列中发热患者血液中的主要病原体,并对其毒力特征进行了研究。共对 718 份来自有发热病史的 IPD/OPD(住院部/门诊部)患者的血样进行了培养,从 83 份培养阳性样本中鉴定出 73 株 。这些分离株对青霉素的耐药性较高,多数为多药耐药株。它们能够形成生物膜,其中 27.4%的分离株为强生物膜生成菌。它们对利奈唑胺、庆大霉素和四环素敏感。这些发现强调了在农村地区预防和管理葡萄球菌感染以及定期进行抗菌药物监测的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acd9/10266288/3654cb40a893/j_pjm-2023-005_fig_001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acd9/10266288/e1162d6d1804/j_pjm-2023-005_fig_002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acd9/10266288/3654cb40a893/j_pjm-2023-005_fig_001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acd9/10266288/e1162d6d1804/j_pjm-2023-005_fig_002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acd9/10266288/3654cb40a893/j_pjm-2023-005_fig_001.jpg

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