Department of Otorhinolaryngology Head and Neck Surgery, Rabin Medical Center - Beilinson Hospital, Petach-Tikva, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Laryngoscope. 2023 Dec;133(12):3299-3303. doi: 10.1002/lary.30685. Epub 2023 Apr 5.
The long-term impact of rhinitis and chronic rhinosinusitis (CRS) on general health and medical services utilization in young adults have been limitedly studied.
A case-control study in the Israeli Defense Forces, between the years 2005 and 2019, of all individuals with either rhinitis or CRS and a matched cohort of healthy individuals with a minimum of 5 years of consecutive follow-up.
The study groups included 617 patients with rhinitis and 296 patients with CRS and 2739 healthy controls with an average age of 28 years. During a mean follow-up of 8 years, a significant fraction of patients in both study groups were diagnosed with asthma compared to the control group, (26.1% and 23.3% vs. 3.7%, respectively; CI 95%: 12.1%-14.9%, p < 0.0001). 7.6% of patients with rhinitis developed CRS. Significantly increased loss of productivity and medical system utilization were noted in the study groups compared to controls (p < 0.0001). Moreover, deterioration in general health, manifested as loss of physical fitness for combative service was observed in a third of patients during follow-up.
Rhinitis and CRS significantly impact productivity and medical service utilization in young adults, as well as general health associated with development of asthma and impairment of physical fitness. A minority of rhinitis patients develop CRS overtime, further affecting this patient group. These patients should be followed up and managed to improve disease control and associated outcomes.
3 Laryngoscope, 133:3299-3303, 2023.
变应性鼻炎和慢性鼻-鼻窦炎（CRS）对年轻人整体健康和医疗服务利用的长期影响研究有限。
这是一项在以色列国防军（IDF）进行的病例对照研究，纳入了 2005 年至 2019 年间患有变应性鼻炎或 CRS 的所有个体，以及与他们相匹配的、至少连续随访 5 年的健康个体队列。
研究组包括 617 例变应性鼻炎患者、296 例 CRS 患者和 2739 例健康对照者，平均年龄为 28 岁。在平均 8 年的随访期间，与对照组相比，两组研究患者中有相当一部分被诊断为哮喘（分别为 26.1%和 23.3%，95%CI：12.1%-14.9%，p<0.0001）。7.6%的变应性鼻炎患者发展为 CRS。与对照组相比，研究组的生产力损失和医疗系统利用率显著增加（p<0.0001）。此外，在随访期间，三分之一的患者出现整体健康状况恶化，表现为丧失战斗服务的体能。
变应性鼻炎和 CRS 显著影响年轻人的生产力和医疗服务利用，以及与哮喘发展和体能受损相关的整体健康。随着时间的推移，少数变应性鼻炎患者会发展为 CRS，这进一步影响了这一患者群体。这些患者应接受随访和管理，以改善疾病控制和相关结局。
3 级 Laryngoscope, 133:3299-3303, 2023.
