电子烟口味的吸引力：从不使用可燃香烟与曾经使用可燃香烟者之间的差异。
Appeal of e-cigarette flavors: Differences between never and ever use of combustible cigarettes.
机构信息
Department of Internal Medicine, The Ohio State University, Columbus, OH, United States; Center for Tobacco Research, The Ohio State University, Columbus, OH, United States.
Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE, United States.
出版信息
Drug Alcohol Depend. 2023 May 1;246:109849. doi: 10.1016/j.drugalcdep.2023.109849. Epub 2023 Mar 23.
BACKGROUND
Characterizing the appeal of flavored e-cigarette solutions by tobacco product use status can inform regulations to reduce vaping in those who never smoked without discouraging adopting e-cigarettes as a quit-smoking aid.
METHODS
Adults aged 21+ who currently use tobacco products (N = 119) self-administered standardized puffs of eight non-tobacco flavored and two tobacco-flavored e-cigarette solutions using a pod-style device. Participants rated appeal (0-100 scale) following each administration. Mean differences in flavor appeal ratings were compared between four groups: people who never smoked/currently vape, formerly smoked/currently vape, currently smoke/currently vape, and currently smoke/do not vape (with interest in vaping).
RESULTS
The Global Flavor (all non-tobacco vs. tobacco)×Group interaction (p = .028) revealed higher appeal for non-tobacco vs. tobacco flavors in adults who never smoked/currently vape (B[95 %CI] = 13.6[4.1-23.1]), formerly smoked/currently vape (B[95 %CI] = 11.6[4.2-18.9]), and currently smoke/currently vape (B[95 %CI] = 9.3[2.5-11.6]), but not adults who currently smoke/never vaped (B[95 %CI] = -0.1[-5.1 to 4.9]). In flavor-specific analyses, adults who never smoked/currently vape rated strawberry (p = .022), peppermint (p = .028), and menthol (p = .028) more appealing than tobacco flavors. Among adults who formerly smoked/currently vape, strawberry (p < .001), peppermint (p = .009), and vanilla (p = .009), were more appealing than tobacco. Adults who currently smoked/currently vape rated peppermint (p = .022) and vanilla (p = .009) as more appealing than tobacco. No non-tobacco flavors were more appealing than tobacco in adults who currently smoke/never vaped.
CONCLUSIONS
E-cigarette sales restrictions on non-tobacco flavors, including menthol, may eliminate products preferred by adults who vape, including those who never smoked, without discouraging adults who currently smoke and never vaped from trying e-cigarettes.
背景
通过对使用烟草制品的人群对调味电子烟溶液的吸引力进行特征描述，可以为减少从未吸烟人群的吸电子烟行为提供监管依据，同时又不会阻碍将电子烟作为戒烟辅助手段的推广。
方法
119 名年龄在 21 岁及以上、当前使用烟草制品的成年人使用一种 pod 样式装置，自行吸食标准化剂量的 8 种非烟草口味和 2 种烟草口味的电子烟溶液。参与者在每次吸食后对吸引力（0-100 分）进行评分。比较从未吸烟/当前吸电子烟、曾经吸烟/当前吸电子烟、当前吸烟/当前吸电子烟、当前吸烟/不吸电子烟（对吸电子烟感兴趣）的四组人群在口味吸引力评分上的差异。
结果
“全球风味（所有非烟草口味与烟草口味）×组间交互”（p =.028）显示，对于从未吸烟/当前吸电子烟（B[95%CI] = 13.6[4.1-23.1]）、曾经吸烟/当前吸电子烟（B[95%CI] = 11.6[4.2-18.9]）和当前吸烟/当前吸电子烟（B[95%CI] = 9.3[2.5-11.6]）的成年人来说，非烟草口味比烟草口味的吸引力更高，但对于当前吸烟/从不吸电子烟的成年人（B[95%CI] = -0.1[-5.1 到 4.9]）并非如此。在口味特异性分析中，从未吸烟/当前吸电子烟的成年人认为草莓（p =.022）、薄荷（p =.028）和薄荷醇（p =.028）比烟草口味更有吸引力。对于曾经吸烟/当前吸电子烟的成年人来说，草莓（p <.001）、薄荷（p =.009）和香草（p =.009）比烟草口味更有吸引力。当前吸烟/当前吸电子烟的成年人认为薄荷（p =.022）和香草（p =.009）比烟草口味更有吸引力。对于当前吸烟/从不吸电子烟的成年人来说，没有任何非烟草口味比烟草口味更受欢迎。
结论
对非烟草口味（包括薄荷醇）电子烟销售的限制，可能会消除包括从未吸烟人群在内的电子烟吸食者喜欢的产品，但不会阻碍当前吸烟且从不吸电子烟的成年人尝试电子烟。
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