Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, Department of Psychology, University of Southern California, Los Angeles, CA, Institute for Addiction Science, University of Southern California Keck School of Medicine, Los Angeles, CA;, Email:
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA.
Am J Health Behav. 2020 Sep 1;44(5):732-743. doi: 10.5993/AJHB.44.5.15.
Effective regulations that reduce nicotine vaping among young adult dual (combustible and e-cigarette) users may differ depending on whether e-cigarettes are used for helping with smoking cessation. This laboratory experiment examined flavor and nicotine effects on e-cigarette product appeal among young adult dual users, stratified by reported use of e-cigarettes to quit smoking. Dual users aged 18-35 years that did (N = 31) or did not (N = 22) report vaping for the purpose of quitting smoking puffed e-cigarette solutions varied by a flavor (fruit, menthol, tobacco) and nicotine (nicotine-containing [6 mg/mL], nicotine-free) with-in-participant design. After puffing each solution, participants rated appeal. In main effect analyses, non-tobacco (vs tobacco) flavors increased appeal and nicotine-containing (vs nicotine free) solutions reduced appeal similarly in dual users who did and did not vape to quit smoking. Interaction analyses found non-significant trend evidence that fruit and menthol flavors suppressed nicotine's appeal-reducing effects more powerfully in those that did not vape to quit smoking (flavor × nicotine × vape to quit smoking, p = .05-.06). Non-tobacco flavors might increase e-cigarette product appeal in young adult dual users overall and disproportionately suppress nicotine's appeal-reducing effects in those that vape for purposes other than assisting with smoking cessation.
有效的监管措施可以减少年轻成年双重使用者（可燃香烟和电子烟）中的尼古丁蒸气，具体取决于电子烟是否用于帮助戒烟。这项实验室实验研究了口味和尼古丁对年轻成年双重使用者电子烟产品吸引力的影响，这些使用者按报告的使用电子烟戒烟的情况进行了分层。18-35 岁的双重使用者中，有（N = 31）或没有（N = 22）报告为了戒烟而吸电子烟，他们通过参与者内设计吸食不同口味（水果、薄荷、烟草）和尼古丁含量（含尼古丁[6 毫克/毫升]、无尼古丁）的电子烟溶液。吸食每种溶液后，参与者会对吸引力进行评分。在主要效应分析中，非烟草（与烟草）口味增加了吸引力，而含尼古丁（与无尼古丁）溶液则降低了吸引力，这种情况在既不吸电子烟也不吸电子烟的双重使用者中是相似的。交互分析发现，在没有吸电子烟戒烟的人中，水果和薄荷口味对尼古丁降低吸引力的效果的抑制作用更为明显（口味×尼古丁×吸电子烟戒烟，p =.05-.06）。非烟草口味可能会增加年轻成年双重使用者对电子烟产品的整体吸引力，并且在那些吸电子烟不是为了帮助戒烟的人中，尼古丁降低吸引力的效果会被不成比例地抑制。
