Rezaei Omolbanin Motamed, Sharifi Farshad, Moodi Mitra, Zarban Asghar, Tahergorabi Reza, Tahergorabi Zoya
Instructor of Environmental Toxicology, Social Determinants of Health Research Center, Department of Occupational Health, School of Health, Birjand University of Medical Sciences, Birjand, Iran.
Department of Geronoto-Epidemiology, Elderly Health Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Int J Prev Med. 2023 Feb 25;14:27. doi: 10.4103/ijpvm.ijpvm_366_21. eCollection 2023.
Aging is identified as a risk factor for vitamin D deficiency (VDD) therefore this investigation was designed to determine the prevalence of VDD and its determinants in a sample of older adults.
The data of this study were obtained from the baseline wave of the Longitudinal Aging Study (LAS). Demographic, past medical history, medication history, and smoking behavior were collected using an interview approach. The physical activity and nutritional status of the participants were assessed using a standard questionnaire. Anthropometric indices were measured according to a standard protocol then body mass index (BMI) was calculated. Serum vitamin D and calcium levels were measured by autoanalyzers. Univariate and multiple logistic regression models were applied to detect the associated factors with VDD.
Mean age of the participants was 71.82 (SD = 7.63) years. A total of 1319 people participated in our study, and 51.16% ( = 688) were female. A total of 8.42% ( = 111) of the participants had VDD and 17.06% of them ( = 225) had insufficient vitamin D levels. In the multivariable logistic regression model, the age group of 70-79 years in comparison with the age group of 60-69 years had a 43% less chance of VDD. Furthermore, being overweight (OR = 0.36, = 0.01) and obese (OR = 0.35, = 0.02), and taking vitamin D supplements (OR = 0.31, = 0.04) were significantly associated with VDD.
Our results showed that 25% of older adults had vitamin D deficiency or insufficiency. In addition, some modifiable lifestyle factors were associated with VDD. Given that, old age is considered a risk factor for VDD. Therefore, detection and improvement of VDD may be a preventive measure in at-risk subjects.
衰老被认为是维生素D缺乏（VDD）的一个风险因素，因此本研究旨在确定老年人群样本中VDD的患病率及其决定因素。
本研究的数据来自纵向衰老研究（LAS）的基线调查。通过访谈收集人口统计学、既往病史、用药史和吸烟行为等信息。使用标准问卷评估参与者的身体活动和营养状况。按照标准方案测量人体测量指标，然后计算体重指数（BMI）。通过自动分析仪测量血清维生素D和钙水平。应用单变量和多变量逻辑回归模型检测与VDD相关的因素。
参与者的平均年龄为71.82（标准差 = 7.63）岁。共有1319人参与我们的研究，其中51.16%（ = 688）为女性。共有8.42%（ = 111）的参与者患有VDD，其中17.06%（ = 225）的维生素D水平不足。在多变量逻辑回归模型中，70 - 79岁年龄组与60 - 69岁年龄组相比，患VDD的几率低43%。此外，超重（比值比 = 0.36， = 0.01）和肥胖（比值比 = 0.35， = 0.02）以及服用维生素D补充剂（比值比 = 0.31， = 0.04）与VDD显著相关。
我们的结果表明，25%的老年人存在维生素D缺乏或不足。此外，一些可改变的生活方式因素与VDD有关。鉴于此，老年被认为是VDD的一个风险因素。因此，检测和改善VDD可能是高危人群的一种预防措施。
