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比尔詹德纵向衰老研究(BLAS):目标、研究方案与设计(第一波:基线数据收集)

Birjand longitudinal aging study (BLAS): the objectives, study protocol and design (wave I: baseline data gathering).

作者信息

Moodi Mitra, Firoozabadi Mohammad Dehghani, Kazemi Tooba, Payab Moloud, Ghaemi Kazem, Miri Mohammad Reza, Sharifzadeh Gholamreza, Fakhrzadeh Hosein, Ebrahimpur Mahbube, Arzaghi Seyed Masoud, Zarban Asghar, Mirimoghadam Ebrahim, Sharifi Ali, Hosseini Motahareh Sheikh, Esmaeili Aliakbar, Mohammadifard Mahyar, Ehsanbakhsh Alireza, Ahmadi Zahra, Yaghoobi Gholam Hossain, Hosseinirad Seyed Abbas, Davari Mohamad Hossein, Heydari Behroz, Nikandish Malihe, Norouzpour Amir, Naseri Saeed, Khorashadizadeh Masoumeh, Mohtashami Somayeh, Mehdizadeh Kambiz, Ahmadi Galileh, Soltani Huriye, Khodbakhshi Huriye, Sharifi Farshad, Larijan Bagher

机构信息

Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.

School of Health, Birjand University of Medical Sciences, Birjand, Iran.

出版信息

J Diabetes Metab Disord. 2020 Mar 5;19(1):551-559. doi: 10.1007/s40200-020-00504-5. eCollection 2020 Jun.

Abstract

OBJECTIVES

The pace of population aging is growing rapidly around the world. Aging is associated with the emergence of different health status including geriatric syndrome such as frailty, diabetes, cardiovascular diseases, and dementia. These conditions are the most prominent challenges for health care systems and also elderly people. Therefore, understanding these changes can help scientists to prevent and treat significant health issues and also improve the ability of

METHODS

This is a protocol of the first wave of Birjand Longitudinal Aging Study that is an ongoing community-based prospective cohort study with a following up at least 10 years. This study carries out on aged population ≥ 60 years which were residents in Birjand County (urban and rural older subjects). The selection of the participants of this study in urban areas is based on an age group weighted multistage stratified random sample while in the rural region the sample was selected from all ten rural regions of Birjand County by simple random sampling. The rural region sampling was based on the list of the aged population which were under the coverage of the rural health center. Sociodemographic, past medical history, lifestyle, sleep, activities of daily living, cognitive function, quality of life, and social capital were evaluated by interviewing with the participants and one of the informants. Anthropometric measures, electrocardiography, and interpretation of ophthalmologic examination were carried out by experts. Fasting Blood samples were collected and bio-banked in - 80 °C. then finally biochemical and hematologic markers were measured.

RESULTS

This is the protocol of stage one baseline of Birjand Longitudinal Aging Study (BLAS). The BLAS is an enjoining study, the first phase of its baseline was carried out on a community- dwelling aged population sample ≥ 60 years who were residents in urban and rural regions of Birjand County. This is a community based prospective cohort study with at least 10 years follow up of participants. The data for 65% of older subjects (response rate = 65%) that lived in clusters were collected.

CONCLUSIONS

This study can help scientists to recognize some risk factors related to the aging process and also aware policymakers about the necessity to create heath care services at regional and even national levels.

摘要

目标

全球人口老龄化速度正在迅速加快。老龄化与包括衰弱、糖尿病、心血管疾病和痴呆等老年综合征在内的不同健康状况的出现相关。这些情况是医疗保健系统以及老年人面临的最突出挑战。因此,了解这些变化有助于科学家预防和治疗重大健康问题,并提高……的能力

方法

这是比尔詹德纵向老龄化研究第一阶段的方案,该研究是一项正在进行的基于社区的前瞻性队列研究,至少随访10年。本研究针对年龄≥60岁的老年人群开展,这些人群是比尔詹德县的居民(城市和农村老年受试者)。本研究城市地区参与者的选择基于年龄组加权多阶段分层随机抽样,而在农村地区,样本通过简单随机抽样从比尔詹德县的所有十个农村地区中选取。农村地区的抽样基于农村卫生中心覆盖范围内的老年人口名单。通过与参与者及一名 informant 进行访谈,对社会人口统计学、既往病史、生活方式、睡眠、日常生活活动、认知功能、生活质量和社会资本进行评估。由专家进行人体测量、心电图检查和眼科检查解读。采集空腹血样并保存在 -80°C 的生物样本库中。然后最终测量生化和血液学指标。

结果

这是比尔詹德纵向老龄化研究(BLAS)第一阶段基线的方案。BLAS 是一项正在进行的研究,其基线的第一阶段是在比尔詹德县城乡地区居住的≥60岁社区老年人群样本上开展的。这是一项基于社区的前瞻性队列研究,对参与者至少随访10年。收集了居住在集群中的65%老年受试者的数据(应答率 = 65%)。

结论

本研究有助于科学家识别一些与衰老过程相关的风险因素,并使政策制定者认识到在地区甚至国家层面创建医疗保健服务的必要性。

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