Bazmamoun Hassan, Momeni Alireza, Jahangard Leila, Asnaashari Farzaneh, Pezeshki Nasrollah
Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran.
Arch Med Sci. 2021 Mar 25;19(2):381-384. doi: 10.5114/aoms/111841. eCollection 2023.
Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children. Functional constipation is common in children and has a significant impact on the quality of their life, affecting both physical and emotional well-being. The aim of this study was to evaluate the frequency of ADHD in functional constipation patients and its treatment effect on constipation.
In this clinical trial study, 80 children with simultaneous ADHD and functional constipation were allocated to two equal groups by the block randomization method. One group was treated only with ADHD drugs and the second group was treated for ADHD and functional constipation. Subsequently, the treatment outcome was evaluated in both groups.
The frequency of ADHD in functional constipation patients was 13.87%. The frequency of functional constipation recovery in the first and second group was respectively 2 (5%) and 39 (97.5%) ( < 0.001). ADHD treatment has no significant effect on the recovery of constipation. There was no statistically significant relationship between the response to treatment with age, sex and duration of having ADHD and constipation.
In patients with simultaneous ADHD and functional constipation, ADHD treatment did not influence the recovery of functional constipation and vice versa.
注意缺陷多动障碍（ADHD）是儿童中最常见的神经发育障碍之一。功能性便秘在儿童中很常见，对他们的生活质量有重大影响，影响身心健康。本研究的目的是评估功能性便秘患者中ADHD的发生率及其对便秘的治疗效果。
在这项临床试验研究中，80名同时患有ADHD和功能性便秘的儿童通过区组随机化方法被分为两组。一组仅接受ADHD药物治疗，第二组同时接受ADHD和功能性便秘的治疗。随后，对两组的治疗结果进行评估。
功能性便秘患者中ADHD的发生率为13.87%。第一组和第二组功能性便秘恢复的发生率分别为2（5%）和39（97.5%）（P<0.001）。ADHD治疗对便秘的恢复没有显著影响。治疗反应与年龄、性别以及患有ADHD和便秘的持续时间之间没有统计学上的显著关系。
在同时患有ADHD和功能性便秘的患者中，ADHD治疗不影响功能性便秘的恢复，反之亦然。
