Iqbal Dure N, Munir Atira, Abbas Mazhar, Nazir Arif, Ali Zahid, Alshawwa Samar Z, Iqbal Munawar, Ahmad Naveed
Department of Chemistry, The University of Lahore, Lahore, Pakistan.
Department of Biochemistry, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Dose Response. 2023 Apr 7;21(2):15593258231169387. doi: 10.1177/15593258231169387. eCollection 2023 Apr-Jun.
Since ancient times, medicinal plants have been used as traditional medicine to treat a variety of ailments. Aloe vera (AV) gel's therapeutic potential is one of the most effective approach in the fabrication of functional materials. The current study aimed to prepare the AV and chitosan (CS) membranes using various cross-linkers that were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform-infrared (FT-IR) spectroscopy, thermal gravimetric analysis (TGA), and ultraviolet-visible (UV-Visible) techniques, as well as swelling ratio and antimicrobial studies. SEM analysis revealed that the membrane is porous, with interconnected pores. The inclusion of AV contents in the membrane improved thermal stability and crystallinity. The swelling ratio of the ACPG-3 membrane with a 2:1 CS to AV ratio was 366%. The membranes showed promising antimicrobial activity against strains. The findings revealed that polymeric CS/AV membranes have effective potential for use in the biomedical field.
自古以来，药用植物就被用作传统药物来治疗各种疾病。芦荟（AV）凝胶的治疗潜力是制造功能材料最有效的方法之一。当前的研究旨在使用各种交联剂制备AV和壳聚糖（CS）膜，并通过X射线衍射（XRD）、扫描电子显微镜（SEM）、傅里叶变换红外（FT-IR）光谱、热重分析（TGA）和紫外可见（UV-Visible）技术以及溶胀率和抗菌研究对其进行表征。SEM分析表明，该膜是多孔的，具有相互连接的孔隙。膜中AV含量的加入提高了热稳定性和结晶度。CS与AV比例为2:1的ACPG-3膜的溶胀率为366%。这些膜对菌株显示出有前景的抗菌活性。研究结果表明，聚合物CS/AV膜在生物医学领域具有有效的应用潜力。
