Department of Mechanical Engineering, University of Texas Rio Grande Valley, Edinburg, TX 78539, USA.
Department of Biology, University of Texas Rio Grande Valley, Edinburg, TX 78539, USA.
Mater Sci Eng C Mater Biol Appl. 2021 May;124:112061. doi: 10.1016/j.msec.2021.112061. Epub 2021 Mar 26.
Natural, biocompatible, and biodegradable composite nanofibers made of Aloe vera extract, pullulan, chitosan, and citric acid were successfully produced via Forcespinning® technology. The addition of Aloe vera extract at different weight percent loadings was investigated. The morphology, thermal properties, physical properties, and water absorption of the nanofibers were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA). The developed nanofiber membranes exhibited good water absorption capabilities, synergistic antibacterial activity against Escherichia coli, and promoted cell attachment and growth. Its porous and high surface area structure make it a potential candidate for wound dressing applications due to its ability to absorb excessive blood and exudates, as well as provide protection from infection while maintaining good thermal stability.
通过 Forcespinning®技术成功制备了由库拉索芦荟提取物、普鲁兰多糖、壳聚糖和柠檬酸组成的天然、生物相容和可生物降解的复合纳米纤维。研究了不同重量百分比负载的库拉索芦荟提取物的添加。使用扫描电子显微镜 (SEM)、傅里叶变换红外光谱 (FTIR) 和热重分析 (TGA) 对纳米纤维的形态、热性能、物理性能和吸水性进行了表征。所开发的纳米纤维膜具有良好的吸水性、对大肠杆菌的协同抗菌活性、促进细胞附着和生长。其多孔和高表面积结构使其成为伤口敷料应用的潜在候选材料，因为它能够吸收过多的血液和渗出物，同时提供抗感染保护，同时保持良好的热稳定性。
