Dong Chenxi, Li Thomas Z, Xu Kaiwen, Wang Zekun, Maldonado Fabien, Sandler Kim, Landman Bennett A, Huo Yuankai
Computer Science, Vanderbilt University, Nashville, TN, USA 37235.
Biomedical Engineering, Vanderbilt University, Nashville, TN, USA 37235.
Proc SPIE Int Soc Opt Eng. 2023 Feb;12469. doi: 10.1117/12.2653626. Epub 2023 Apr 10.
Artificial intelligence (AI) has been widely introduced to various medical imaging applications ranging from disease visualization to medical decision support. However, data privacy has become an essential concern in clinical practice of deploying the deep learning algorithms through cloud computing. The sensitivity of patient health information (PHI) commonly limits network transfer, installation of bespoke desktop software, and access to computing resources. Serverless edge-computing shed light on privacy preserved model distribution maintaining both high flexibility (as cloud computing) and security (as local deployment). In this paper, we propose a browser-based, cross-platform, and privacy preserved medical imaging AI deployment system working on consumer-level hardware via serverless edge-computing. Briefly we implement this system by deploying a 3D medical image segmentation model for computed tomography (CT) based lung cancer screening. We further curate tradeoffs in model complexity and data size by characterizing the speed, memory usage, and limitations across various operating systems and browsers. Our implementation achieves a deployment with (1) a 3D convolutional neural network (CNN) on CT volumes (256×256×256 resolution), (2) an average runtime of 80 seconds across Firefox v.102.0.1/Chrome v.103.0.5060.114/Microsoft Edge v.103.0.1264.44 and 210 seconds on Safari v.14.1.1, and (3) an average memory usage of 1.5 GB on Microsoft Windows laptops, Linux workstation, and Apple Mac laptops. In conclusion, this work presents a privacy-preserved solution for medical imaging AI applications that minimizes the risk of PHI exposure. We characterize the tools, architectures, and parameters of our framework to facilitate the translation of modern deep learning methods into routine clinical care.
人工智能(AI)已被广泛应用于从疾病可视化到医疗决策支持的各种医学成像应用中。然而,在通过云计算部署深度学习算法的临床实践中,数据隐私已成为一个至关重要的问题。患者健康信息(PHI)的敏感性通常限制了网络传输、定制桌面软件的安装以及对计算资源的访问。无服务器边缘计算为隐私保护模型分发带来了曙光,它同时保持了高灵活性(如云计算)和安全性(如本地部署)。在本文中,我们提出了一种基于浏览器的、跨平台的、隐私保护的医学成像AI部署系统,该系统通过无服务器边缘计算在消费级硬件上运行。简要地说,我们通过部署用于基于计算机断层扫描(CT)的肺癌筛查的3D医学图像分割模型来实现这个系统。我们通过描述各种操作系统和浏览器的速度、内存使用情况及限制,进一步在模型复杂性和数据大小之间进行权衡。我们的实现达成了以下部署:(1)在CT容积(256×256×256分辨率)上使用3D卷积神经网络(CNN);(2)在Firefox v.102.0.1/Chrome v.103.0.5060.114/Microsoft Edge v.103.0.1264.44上平均运行时间为80秒,在Safari v.14.1.1上为210秒;(3)在Microsoft Windows笔记本电脑、Linux工作站和Apple Mac笔记本电脑上平均内存使用量为1.5GB。总之,这项工作为医学成像AI应用提出了一种隐私保护解决方案,将PHI暴露的风险降至最低。我们描述了我们框架的工具、架构和参数,以促进现代深度学习方法转化为常规临床护理。