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脑肿瘤检测与分割:具有可视化界面和反馈功能的交互式框架,可动态提高准确性和可信度。

Brain tumor detection and segmentation: Interactive framework with a visual interface and feedback facility for dynamically improved accuracy and trust.

机构信息

Department of Computer Science, University of Calgary, Alberta, Canada.

Department of Computer Engineering, Istanbul Medipol University, Istanbul, Turkey.

出版信息

PLoS One. 2023 Apr 17;18(4):e0284418. doi: 10.1371/journal.pone.0284418. eCollection 2023.

Abstract

Brain cancers caused by malignant brain tumors are one of the most fatal cancer types with a low survival rate mostly due to the difficulties in early detection. Medical professionals therefore use various invasive and non-invasive methods for detecting and treating brain tumors at the earlier stages thus enabling early treatment. The main non-invasive methods for brain tumor diagnosis and assessment are brain imaging like computed tomography (CT), positron emission tomography (PET) and magnetic resonance imaging (MRI) scans. In this paper, the focus is on detection and segmentation of brain tumors from 2D and 3D brain MRIs. For this purpose, a complete automated system with a web application user interface is described which detects and segments brain tumors with more than 90% accuracy and Dice scores. The user can upload brain MRIs or can access brain images from hospital databases to check presence or absence of brain tumor, to check the existence of brain tumor from brain MRI features and to extract the tumor region precisely from the brain MRI using deep neural networks like CNN, U-Net and U-Net++. The web application also provides an option for entering feedbacks on the results of the detection and segmentation to allow healthcare professionals to add more precise information on the results that can be used to train the model for better future predictions and segmentations.

摘要

由恶性脑瘤引起的脑癌是最致命的癌症类型之一,由于早期检测困难,生存率通常很低。因此,医疗专业人员使用各种侵入性和非侵入性方法在早期检测和治疗脑瘤,从而实现早期治疗。脑肿瘤诊断和评估的主要非侵入性方法是脑成像,如计算机断层扫描 (CT)、正电子发射断层扫描 (PET) 和磁共振成像 (MRI) 扫描。本文重点介绍从 2D 和 3D 脑部 MRI 中检测和分割脑肿瘤。为此,描述了一个具有 Web 应用程序用户界面的完整自动化系统,该系统可以以超过 90%的准确率和骰子分数检测和分割脑肿瘤。用户可以上传脑部 MRI,也可以从医院数据库访问脑部图像,以检查是否存在脑肿瘤,从脑部 MRI 特征检查是否存在脑肿瘤,并使用卷积神经网络 (CNN)、U-Net 和 U-Net++等深度神经网络从脑部 MRI 中精确提取肿瘤区域。Web 应用程序还提供了输入检测和分割结果反馈的选项,允许医疗保健专业人员添加更准确的信息,这些信息可用于训练模型,以实现更好的未来预测和分割。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f8/10109523/1bba27d2d52f/pone.0284418.g001.jpg

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