JBrowse 2：一个具有基因同线性和结构变异视图的模块化基因组浏览器。
JBrowse 2: a modular genome browser with views of synteny and structural variation.
机构信息
Department of Bioengineering, Stanley Hall, University of California, Berkeley, CA, 94720, USA.
Adaptive Oncology, Ontario Institute for Cancer Research, MaRS Centre, 661 University Avenue, Suite 510, Toronto, ON, M5G 0A3, Canada.
出版信息
Genome Biol. 2023 Apr 17;24(1):74. doi: 10.1186/s13059-023-02914-z.
We present JBrowse 2, a general-purpose genome annotation browser offering enhanced visualization of complex structural variation and evolutionary relationships. It retains core features of JBrowse while adding new views for synteny, dotplots, breakpoints, gene fusions, and whole-genome overviews. It allows users to share sessions, open multiple genomes, and navigate between views. It can be embedded in a web page, used as a standalone application, or run from Jupyter notebooks or R sessions. These improvements are enabled by a ground-up redesign using modern web technology. We describe application functionality, use cases, performance benchmarks, and implementation notes for web administrators and developers.
我们介绍 JBrowse 2，这是一个通用的基因组注释浏览器，提供了增强的复杂结构变异和进化关系可视化功能。它保留了 JBrowse 的核心功能，同时增加了用于基因同线性、点图、断点、基因融合和全基因组概览的新视图。它允许用户共享会话、打开多个基因组，并在视图之间进行导航。它可以嵌入网页中，作为独立的应用程序使用，也可以从 Jupyter 笔记本或 R 会话中运行。这些改进是通过使用现代 Web 技术进行全面重新设计实现的。我们描述了应用程序功能、用例、性能基准测试以及网络管理员和开发人员的实现说明。
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