克拉维酸、阿莫西林和替卡西林对沙眼衣原体的体外活性。
In vitro activity of clavulanic acid, amoxicillin, and ticarcillin against Chlamydia trachomatis.
作者信息
Bowie W R
出版信息
Antimicrob Agents Chemother. 1986 Apr;29(4):713-5. doi: 10.1128/AAC.29.4.713.
Abstract
In vitro, growth of Chlamydia trachomatis was not entirely eliminated by 960 micrograms of ticarcillin per ml, 64 micrograms of amoxicillin per ml, 32 micrograms of clavulanic acid per ml, a combination of ticarcillin (480 micrograms/ml) and clavulanic acid (32 micrograms/ml), and a combination of amoxicillin (32 micrograms/ml) and clavulanic acid (8 micrograms/ml). However, a greater than or equal to 99% decrease in the number of inclusions was obtained at concentrations readily attainable in serum.
摘要
在体外，每毫升960微克的替卡西林、每毫升64微克的阿莫西林、每毫升32微克的克拉维酸、替卡西林（每毫升480微克）与克拉维酸（每毫升32微克）的组合以及阿莫西林（每毫升32微克）与克拉维酸（每毫升8微克）的组合均不能完全消除沙眼衣原体的生长。然而，在血清中易于达到的浓度下，包涵体数量减少了99%或更多。
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