Dang Brittany Q, Miles Brittany, Young Peter, He Jing, Nguyen Quan D
Radiology, University of Texas Medical Branch, Galveston, USA.
Pathology, University of Texas Medical Branch, Galveston, USA.
Cureus. 2023 Mar 17;15(3):e36292. doi: 10.7759/cureus.36292. eCollection 2023 Mar.
Fibrocystic changes (FCCs) are common, often benign, breast lesions characterized by adenosis, fibrosis, and cyst formation. These changes are believed to be associated with fluctuating hormone levels and are predominantly found in premenopausal women due to higher levels of estrogen. Certain conditions that cause hormonal imbalances, such as polycystic ovarian syndrome, have also been associated with an increased risk of FCCs. FCCs can occur in postmenopausal women on hormonal replacement therapy but are otherwise extremely rare. Although this condition is primarily considered benign, complex cysts presenting in a rare demographic warrant further evaluation beyond screening mammograms to exclude the possibility of malignancy. In this paper, we present the case of new FCCs in a postmenopausal woman and explore the radiology, histology, carcinogenic potential, treatment options, and potential contributing factors of the condition.
纤维囊性改变（FCCs）是常见的、通常为良性的乳腺病变，其特征为腺病、纤维化和囊肿形成。这些改变被认为与激素水平波动有关，主要见于绝经前女性，因为她们的雌激素水平较高。某些导致激素失衡的疾病，如多囊卵巢综合征，也与FCCs风险增加有关。FCCs可发生于接受激素替代治疗的绝经后女性，但在其他情况下极为罕见。尽管这种情况主要被认为是良性的，但在罕见人群中出现的复杂囊肿需要在乳腺钼靶筛查之外进行进一步评估，以排除恶性肿瘤的可能性。在本文中，我们介绍了一名绝经后女性新发FCCs的病例，并探讨了该疾病的放射学、组织学、致癌潜力、治疗选择和潜在促成因素。
