Vittorakis Eftychios, Vică Mihaela Laura, Zervaki Calina Oana, Vittorakis Evangelos, Maraki Sofia, Mavromanolaki Viktoria Eirini, Schürger Michael Ewald, Neculicioiu Vlad Sever, Papadomanolaki Evangelia, Sinanis Theodoros, Giannoulaki Georgia, Xydaki Evangelia, Kastanakis Serafeim G, Junie Lia Monica
Department of Microbiology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Department of Cell and Molecular Biology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Microorganisms. 2023 Mar 25;11(4):841. doi: 10.3390/microorganisms11040841.
is a pathogenic bacterium that causesinfections. Its virulence is due to surface components, proteins, virulence genes, , , , and , which are low molecular weight superantigens. are usually encoded by mobile genetic elements, and horizontal gene transfer accounts for their widespread presence in . This study analyzed the prevalence of MRSA and MSSA strains of in two hospitals in Greece between 2020-2022 and their susceptibility to antibiotics. Specimens collected were tested using the VITEK 2 system and the PCR technique to detect types, types, genes, and and genes. Antibiotics from various classes were also tested. This study examined the prevalence and resistance of strains in hospitals. It found a high prevalence of MRSA and that the MRSA strains were more resistant to antibiotics. The study also identified the genotypes of the isolates and the associated antibiotic resistances. This highlights the need for continued surveillance and effective strategies to combat the spread of MRSA in hospitals. This study examined the prevalence of the gene and its co-occurrence with other genes in strains, as well as their antibiotic susceptibility. The results showed that 19.15% of the isolates were -positive and 80.85% were -negative. The gene co-existed with other genes, such as the and enterotoxin genes. The results could inform treatment strategies for infections.
是一种引起感染的致病细菌。其毒力归因于表面成分、蛋白质、毒力基因,以及低分子量超抗原等。通常由可移动遗传元件编码,水平基因转移导致它们在广泛存在。本研究分析了2020 - 2022年希腊两家医院中该菌的耐甲氧西林金黄色葡萄球菌(MRSA)和甲氧西林敏感金黄色葡萄球菌(MSSA)菌株的流行情况及其对抗生素的敏感性。使用VITEK 2系统和PCR技术对采集的标本进行检测,以检测该菌的类型、型别、基因以及和基因。还对各类抗生素进行了测试。本研究调查了医院中该菌菌株的流行情况和耐药性。发现MRSA的流行率很高,且MRSA菌株对抗生素的耐药性更强。该研究还确定了该菌分离株的基因型以及相关的抗生素耐药性。这突出了持续监测和采取有效策略以对抗医院中MRSA传播的必要性。本研究调查了该菌菌株中基因的流行情况及其与其他基因的共现情况,以及它们的抗生素敏感性。结果显示,19.15%的分离株为阳性,80.85%为阴性。该基因与其他基因共存,如和肠毒素基因。这些结果可为该菌感染的治疗策略提供参考。