Ji Min-Jeong, Cho Hyung-Chul, Park Yu-Jin, Jang Dong-Hun, Park Jinho, Choi Kyoung-Seong
Department of Animal Science and Biotechnology, College of Ecology and Environmental Science, Kyungpook National University, Sangju 37224, Republic of Korea.
College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Republic of Korea.
Pathogens. 2023 Apr 1;12(4):547. doi: 10.3390/pathogens12040547.
, a major zoonotic pathogen distributed worldwide, causes severe infections in humans, animals, and birds. However, limited information is available regarding infection in livestock in the Republic of Korea (ROK). Herein, we determined the prevalence of infection in livestock in the ROK and identified animal species that can potentially transmit to humans. gene-targeting nested polymerase chain reaction detected DNA in 3.3% (2/61), 2.9% (3/105), 14.1% (11/78), and 15.4% (14/91) of dairy cattle, beef cattle, Boer goats, and Korean native goats, respectively. The prevalence of was significantly higher ( = 0.002) in goats than in cattle. The risk of contracting infection was significantly higher by 6.18-fold in Korean native goats (95% confidence interval [CI]: 1.72-22.27%, = 0.005) and by 5.58-fold in Boer goats (95% CI: 1.50-20.76%, = 0.010) than in beef cattle. Our DNA sequences exhibited 97.1-100% homology with those obtained from various hosts in other countries. To the best of our knowledge, this is the first study to report infection using the blood samples of domestic ruminants in the ROK. The results revealed that the prevalence of infection is higher in goats than in cattle as determined by molecular detection. Thus, these findings suggest that can be transmitted from ruminants to humans via meat consumption.
是一种分布于全球的主要人畜共患病原体，可导致人类、动物和禽类发生严重感染。然而，关于大韩民国（韩国）家畜感染的信息有限。在此，我们确定了韩国家畜感染的流行情况，并确定了可能将传播给人类的动物种类。基因靶向巢式聚合酶链反应分别在3.3%（2/61）的奶牛、2.9%（3/105）的肉牛、14.1%（11/78）的布尔山羊和15.4%（14/91）的韩国本地山羊中检测到DNA。山羊中的感染率显著高于牛（P = 0.002）。韩国本地山羊感染的风险比肉牛高6.18倍（95%置信区间[CI]：1.72 - 22.27%，P = 0.005），布尔山羊比肉牛高5.58倍（95%CI：1.50 - 20.76%，P = 0.010）。我们的DNA序列与从其他国家不同宿主获得的序列具有97.1 - 100%的同源性。据我们所知，这是第一项使用韩国家养反刍动物血液样本报告感染情况的研究。结果表明，通过分子检测确定，山羊中的感染率高于牛。因此，这些发现表明可通过食用肉类从反刍动物传播给人类。
