Institute of Vertebrate Biology, Czech Academy of Sciences, Květná 8, Brno, 603 65, Czech Republic.
Center for Virology, Medical University of Vienna, Kinderspitalgasse 15, Vienna, 1095, Austria.
Zoonoses Public Health. 2023 Aug;70(5):371-382. doi: 10.1111/zph.13042. Epub 2023 May 2.
Ťahyňa virus (TAHV) is an orthobunyavirus and was the first arbovirus isolated from mosquitoes in Europe and is associated with floodplain areas as a characteristic biotope, hares as reservoir hosts and the mammal-feeding mosquitoes Aedes vexans as the main vector. The disease caused by TAHV ("Valtice fever") was detected in people with acute flu-like illness in the 1960s, and later the medical significance of TAHV became the subject of many studies. Although TAHV infections are widespread, the prevalence and number of actual cases, clinical manifestations in humans and animals and the ecology of transmission by mosquitoes and their vertebrate hosts are rarely reported. Despite its association with meningitis in humans, TAHV is a neglected human pathogen with unknown public health importance in Central Europe, and a potential emerging disease threat elsewhere in Europe due to extreme summer flooding events.
塔雅尼病毒（TAHV）是一种正布尼亚病毒，是在欧洲从蚊子中分离出来的第一种虫媒病毒，与洪泛区作为特征生境、野兔作为储存宿主以及以哺乳动物为食的伊蚊 Aedes vexans 作为主要传播媒介有关。20 世纪 60 年代，在出现急性流感样疾病的人群中发现了由 TAHV（“瓦尔季采热”）引起的疾病，此后，TAHV 的医学意义成为许多研究的主题。尽管 TAHV 感染很普遍，但蚊子及其脊椎动物宿主的传播流行率、实际病例数、人类和动物中的临床表现以及生态学很少有报道。尽管 TAHV 与人患脑膜炎有关，但它是一种被忽视的人类病原体，在中欧的公共卫生重要性未知，在欧洲其他地区，由于夏季极端洪水事件，它是一种潜在的新出现疾病威胁。
