Zhejiang University, Hangzhou, China.
Zhejiang University School of Public Health, Hangzhou, China.
Am J Alzheimers Dis Other Demen. 2023 Jan-Dec;38:15333175231167118. doi: 10.1177/15333175231167118.
To investigate the independent and synergistic associations between abdominal obesity, chewing difficulty and cognitive impairment in a community-dwelling older adults sample in China.
Cognitive function was measured by the 5 min- Montreal Cognitive Assessment (5 min-MoCA) and abdominal obesity was measured by A Body Shape Index (ABSI) in 572 participants recruited from local communities. Chewing difficulty was assessed via a self-report questionnaire. Linear regression and general logistic regression were performed to investigate the association of chewing difficulty and abdominal obesity with cognition.
Chewing difficulty score [β (95% CI) = -.30 (-.49, -.11)] and ABSI [β (95%CI) = -.30 (-.55, -.05)] were independently associated with worse performance on the 5 min-MoCA. Whilst ABSI was not associated with cognitive impairment, the co-existence of chewing difficulty and abdominal obesity [OR (95% CI) = 2.22 (1.18, 4.17)] was found associated with the presence of cognitive impairment.
Chewing difficulty and abdominal obesity were independently associated with cognition. Abdominal obesity and chewing may have an additive effect on cognitive function.
在中国社区老年人样本中，研究腹部肥胖、咀嚼困难与认知障碍之间的独立和协同关联。
在 572 名来自当地社区的参与者中，通过 5 分钟蒙特利尔认知评估（5 min-MoCA）来测量认知功能，通过体脂分布指数（ABSI）来测量腹部肥胖。通过自我报告问卷评估咀嚼困难程度。采用线性回归和一般逻辑回归来研究咀嚼困难和腹部肥胖与认知之间的关联。
咀嚼困难评分[β（95%CI）= -.30（-.49，-.11）]和 ABSI[β（95%CI）= -.30（-.55，-.05）]与 5 min-MoCA 表现较差独立相关。虽然 ABSI 与认知障碍无关，但咀嚼困难和腹部肥胖同时存在[OR（95%CI）= 2.22（1.18，4.17）]与认知障碍的发生相关。
咀嚼困难和腹部肥胖与认知功能独立相关。腹部肥胖和咀嚼可能对认知功能有相加作用。
