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胃肠道的激光组织焊接:一项关于胃肠道激光组织焊接的系统评价

Laser tissue soldering of the gastrointestinal tract: A systematic review LTS of the gastrointestinal tract.

作者信息

Ashbell Ido, Agam Nadav, Katzir Abraham, Basov Svetlana, Platkov Max, Avital Itzhak, Nisky Ilana, Netz Uri

机构信息

Goldman School of Medicine, Ben Gurion University, Beer-Sheva, Israel.

School of Physics & Astronomy, Tel Aviv University, Tel Aviv, Israel.

出版信息

Heliyon. 2023 May 1;9(5):e16018. doi: 10.1016/j.heliyon.2023.e16018. eCollection 2023 May.

Abstract

BACKGROUND

Laser Tissue Soldering (LTS) is a promising tissue bonding technique in which a solder is applied between the tissues and then irradiated by laser, causing it to solidify and form links with the tissue.

METHODS

A comprehensive systematic review summarizing the state of research of LTS in the gastrointestinal tract.

RESULTS

Most studies were conducted on large animal tissues, using liquid proteinaceous solder, and irradiated by a continuous wave laser at 808 nm. LTS can provide better sealing and burst pressure than conventional methods. The application of LTS on top of or in addition to sutures showed an impressive increase in burst pressures. LTS may decrease the inflammatory and foreign body reaction caused by sutures.

CONCLUSIONS

LTS has strong potential to be applied in a clinical setting in leak prevention and in closure of gastrointestinal structures as an adjunct or additional anastomotic technology, decreasing leak rates, morbidity, and mortality.

摘要

背景

激光组织焊接(LTS)是一种很有前景的组织粘合技术,即在组织之间涂抹焊料,然后用激光照射,使其凝固并与组织形成连接。

方法

对胃肠道中激光组织焊接的研究现状进行全面的系统综述。

结果

大多数研究是在大型动物组织上进行的,使用液体蛋白质焊料,并由808纳米的连续波激光照射。与传统方法相比,激光组织焊接能提供更好的密封效果和爆破压力。在缝合线之上或之外应用激光组织焊接,爆破压力有显著提高。激光组织焊接可能会减少缝合线引起的炎症和异物反应。

结论

作为一种辅助或额外的吻合技术,激光组织焊接在预防渗漏和闭合胃肠道结构方面具有很强的临床应用潜力,可降低渗漏率、发病率和死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01b6/10189270/9375c94ce1fd/gr1.jpg

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