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代谢性疾病中外泌体的知识图谱：文献计量分析（2007-2022 年）。

Knowledge mapping of exosomes in metabolic diseases: a bibliometric analysis (2007-2022).

机构信息

The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital, National Center of Gerontology of National Health Commission, Beijing, China.

Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

Front Endocrinol (Lausanne). 2023 May 8;14:1176430. doi: 10.3389/fendo.2023.1176430. eCollection 2023.

DOI:10.3389/fendo.2023.1176430
PMID:37223047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10200891/
Abstract

BACKGROUND: Research on exosomes in metabolic diseases has been gaining attention, but a comprehensive and objective report on the current state of research is lacking. This study aimed to conduct a bibliometric analysis of publications on "exosomes in metabolic diseases" to analyze the current status and trends of research using visualization methods. METHODS: The web of science core collection was searched for publications on exosomes in metabolic diseases from 2007 to 2022. Three software packages, VOSviewer, CiteSpace, and R package "bibliometrix" were used for the bibliometric analysis. RESULTS: A total of 532 papers were analyzed, authored by 29,705 researchers from 46 countries/regions and 923 institutions, published in 310 academic journals. The number of publications related to exosomes in metabolic diseases is gradually increasing. China and the United States were the most productive countries, while Ciber Centro de Investigacion Biomedica en Red was the most active institution. published the most relevant studies, and received the most citations. Khalyfa, Abdelnaby published the most papers and Thery, C was the most cited. The ten most co-cited references were considered as the knowledge base. After analysis, the most common keywords were microRNAs, biomarkers, insulin resistance, expression, and obesity. Applying basic research related on exosomes in metabolic diseases to clinical diagnosis and treatment is a research hotspot and trend. CONCLUSION: This study provides a comprehensive summary of research trends and developments in exosomes in metabolic diseases through bibliometrics. The information points out the research frontiers and hot directions in recent years and will provide a reference for researchers in this field.

摘要

背景：代谢性疾病中有关外泌体的研究受到了广泛关注，但目前缺乏对该领域研究现状的全面和客观的报告。本研究旨在通过可视化方法对“代谢性疾病中外泌体”的研究文献进行计量学分析，以分析研究现状和趋势。

方法：检索 2007 年至 2022 年在科学引文索引核心集上发表的代谢性疾病中外泌体相关文献，使用 VOSviewer、CiteSpace 和 R 包“bibliometrix”三个软件包进行文献计量学分析。

结果：共分析了 532 篇论文，作者来自 46 个国家/地区和 923 个机构的 29705 名研究人员，发表在 310 种学术期刊上。与代谢性疾病中外泌体相关的出版物数量逐渐增加。中国和美国是最具生产力的国家，而 Ciber Centro de Investigacion Biomedica en Red 是最活跃的机构。Diabetes 发表的相关研究最多，而 Nature 获得的引用最多。Khalyfa, Abdelnaby 发表的论文最多，而 Thery, C 被引用最多。前 10 个共被引文献被视为知识库。分析后，最常见的关键词是 microRNAs、生物标志物、胰岛素抵抗、表达和肥胖。将与代谢性疾病中外泌体相关的基础研究应用于临床诊断和治疗是一个研究热点和趋势。

结论：本研究通过计量学方法对代谢性疾病中外泌体的研究趋势和进展进行了全面总结。这些信息指出了近年来的研究前沿和热点方向，将为该领域的研究人员提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/f29f12724d09/fendo-14-1176430-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/1b6f91ffc984/fendo-14-1176430-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/9fb1d9e5bf92/fendo-14-1176430-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/2da81d64e859/fendo-14-1176430-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/84c94459ed49/fendo-14-1176430-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/00c3743f02ac/fendo-14-1176430-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/9afa7703adda/fendo-14-1176430-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/5f5147936eb0/fendo-14-1176430-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/b6bfab9357a6/fendo-14-1176430-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/f29f12724d09/fendo-14-1176430-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/1b6f91ffc984/fendo-14-1176430-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/9fb1d9e5bf92/fendo-14-1176430-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/2da81d64e859/fendo-14-1176430-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/84c94459ed49/fendo-14-1176430-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/00c3743f02ac/fendo-14-1176430-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/9afa7703adda/fendo-14-1176430-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/5f5147936eb0/fendo-14-1176430-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/b6bfab9357a6/fendo-14-1176430-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c9e/10200891/f29f12724d09/fendo-14-1176430-g009.jpg

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本文引用的文献

[1]
Knowledge domain and emerging trends in beta-cell research: A bibliometric and knowledge-map analysis.

Front Endocrinol (Lausanne). 2022

[2]
Knowledge Mapping of Exosomes in Autoimmune Diseases: A Bibliometric Analysis (2002-2021).

Front Immunol. 2022

[3]
Alternative therapeutic strategy for existing aortic aneurysms using mesenchymal stem cell-derived exosomes.

Expert Opin Biol Ther. 2022-1

[4]
Exosomes as mediators of intercellular crosstalk in metabolism.

Cell Metab. 2021-9-7

[5]
Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9.

Nat Commun. 2021-7-19

[6]
Ferritinophagy and ferroptosis in the management of metabolic diseases.

Trends Endocrinol Metab. 2021-7

[7]
The Mystery of Red Blood Cells Extracellular Vesicles in Sleep Apnea with Metabolic Dysfunction.

Int J Mol Sci. 2021-4-21

[8]
Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3.

Cell Rep. 2021-1-5

[9]
Developmental origins of metabolic diseases.

Physiol Rev. 2021-7-1

[10]
A bibliometric analysis of periodontology.

Periodontol 2000. 2021-2

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