Monson J P, Koios G, Toms G C, Kopelman P G, Boucher B J, Evans S J, Alexander W L
J R Soc Med. 1986 May;79(5):274-6. doi: 10.1177/014107688607900506.
The possible relationship between antecedent diabetic control, as determined by serial glycosylated haemoglobin (HbA1) measurements, and diabetic retinopathy was examined in 40 insulin-dependent and 41 non-insulin-dependent diabetics selected consecutively from our clinic population. Multiple logistic regression analysis demonstrated a significant association between mean HbA1 and prevalence of retinopathy in both groups of patients. This association was independent of duration of diabetes which was also significantly associated with retinopathy prevalence. Hypertension and smoking were not obvious risk factors in this group of patients; an apparent association of hypertension and diabetes was entirely accounted for by a positive relationship between the presence of hypertension and duration of diabetes.
通过连续测量糖化血红蛋白（HbA1）来确定的前期糖尿病控制情况与糖尿病视网膜病变之间的可能关系，在从我们诊所人群中连续选取的40名胰岛素依赖型糖尿病患者和41名非胰岛素依赖型糖尿病患者中进行了研究。多因素逻辑回归分析表明，两组患者的平均HbA1与视网膜病变患病率之间存在显著关联。这种关联独立于糖尿病病程，而糖尿病病程也与视网膜病变患病率显著相关。高血压和吸烟在这组患者中并非明显的危险因素；高血压与糖尿病之间明显的关联完全是由高血压的存在与糖尿病病程之间的正相关关系所导致的。
