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腹部瘀斑:紧急情况,还是紧急-常规情况?

Abdominal Ecchymosis: Emergency, or Urgen-C?

作者信息

Jones Riley, Shafiq Leila, Idowu Benmichael, Radhakrishnan Nila S, Fromm Jason

机构信息

Medicine, University of Florida College of Medicine, Gainesville, USA.

Medicine, University of South Florida Morsani College of Medicine, Tampa, USA.

出版信息

Cureus. 2023 Apr 25;15(4):e38091. doi: 10.7759/cureus.38091. eCollection 2023 Apr.

DOI:10.7759/cureus.38091
PMID:37252579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10209748/
Abstract

Scurvy is a multisystem disease caused by vitamin C deficiency, historically associated with lethargy, gingivitis, ecchymosis, edema, and death if left untreated. Contemporary socioeconomic risk factors for scurvy include smoking, alcohol abuse, fad diets, mental health conditions, social isolation, and economic marginalization. Food insecurity is also a risk factor. This report describes a case of a man in his 70s who presented with unexplained dyspnea, abdominal pain, and abdominal ecchymosis. His plasma vitamin C level was undetectable, and he improved with vitamin C supplementation. This case highlights the significance of awareness of these risk factors and emphasizes the need for a comprehensive social and dietary history to enable the timely treatment of this rare but potentially fatal disease.

摘要

坏血病是一种由维生素C缺乏引起的多系统疾病,在历史上,如果不治疗,会出现嗜睡、牙龈炎、瘀斑、水肿甚至死亡。当代坏血病的社会经济风险因素包括吸烟、酗酒、时尚饮食、心理健康问题、社会孤立和经济边缘化。粮食不安全也是一个风险因素。本报告描述了一名70多岁男性的病例,他出现了不明原因的呼吸困难、腹痛和腹部瘀斑。他的血浆维生素C水平检测不到,补充维生素C后病情有所改善。该病例突出了认识这些风险因素的重要性,并强调需要全面了解社会和饮食史,以便及时治疗这种罕见但可能致命的疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/fba1bd8e440a/cureus-0015-00000038091-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/ae93df456354/cureus-0015-00000038091-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/c6ebc4c5c656/cureus-0015-00000038091-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/d0c53f34bb9a/cureus-0015-00000038091-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/e1df40e2927d/cureus-0015-00000038091-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/ff82cf7fccba/cureus-0015-00000038091-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/fba1bd8e440a/cureus-0015-00000038091-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/ae93df456354/cureus-0015-00000038091-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/c6ebc4c5c656/cureus-0015-00000038091-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/d0c53f34bb9a/cureus-0015-00000038091-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/e1df40e2927d/cureus-0015-00000038091-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/ff82cf7fccba/cureus-0015-00000038091-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e00b/10209748/fba1bd8e440a/cureus-0015-00000038091-i06.jpg

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本文引用的文献

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An Epidemic of Scurvy, Identified Based on Lower Extremity Swelling, in a Southern Ethiopian Prison.在埃塞俄比亚南部一所监狱中,根据下肢肿胀发现了坏血病流行。
Am J Trop Med Hyg. 2021 Jun 28;105(2):511-516. doi: 10.4269/ajtmh.20-1246.
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Nutrients. 2020 Jul 1;12(7):1963. doi: 10.3390/nu12071963.
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An Atomic Force Microscopy Study on the Effect of β-Galactosidase, α-L-Rhamnosidase and α-L-Arabinofuranosidase on the Structure of Pectin Extracted from Apple Fruit Using Sodium Carbonate.
采用碳酸钠提取的苹果果胶的结构受β-半乳糖苷酶、α-L-鼠李糖苷酶和α-L-阿拉伯呋喃糖苷酶影响的原子力显微镜研究
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Modern-day scurvy.现代坏血病
CMAJ. 2020 Jan 27;192(4):E96. doi: 10.1503/cmaj.190934.
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The Roles of Vitamin C in Skin Health.维生素 C 在皮肤健康中的作用。
Nutrients. 2017 Aug 12;9(8):866. doi: 10.3390/nu9080866.
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Vitamin C supplementation for the primary prevention of cardiovascular disease.补充维生素C用于心血管疾病的一级预防。
Cochrane Database Syst Rev. 2017 Mar 16;3(3):CD011114. doi: 10.1002/14651858.CD011114.pub2.
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Impact of high dose vitamin C on platelet function.高剂量维生素C对血小板功能的影响。
World J Crit Care Med. 2017 Feb 4;6(1):37-47. doi: 10.5492/wjccm.v6.i1.37.
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High Dietary Fructose Intake on Cardiovascular Disease Related Parameters in Growing Rats.高膳食果糖摄入量对生长中大鼠心血管疾病相关参数的影响
Nutrients. 2016 Dec 26;9(1):11. doi: 10.3390/nu9010011.
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Determination of plasma and leukocyte vitamin C concentrations in a randomized, double-blind, placebo-controlled trial with Ester-C(®).在一项使用酯化维生素C(Ester-C(®))的随机、双盲、安慰剂对照试验中测定血浆和白细胞中的维生素C浓度。
Springerplus. 2016 Jul 25;5(1):1161. doi: 10.1186/s40064-016-2605-7. eCollection 2016.
10
Ascorbate as a co-factor for fe- and 2-oxoglutarate dependent dioxygenases: physiological activity in tumor growth and progression.抗坏血酸作为铁依赖型和 2-氧代戊二酸依赖型双加氧酶的辅助因子:在肿瘤生长和进展中的生理活性。
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