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LS 900 测量大量儿童和青少年眼生物参数的可行性和可重复性。

Feasibility and repeatability of ocular biometry measured with Lenstar LS 900 in a large group of children and adolescents.

机构信息

Institute for Medical Informatics, Statistics, and Epidemiology (IMISE), Leipzig University, Leipzig, Germany.

Leipzig Research Centre for Civilization Diseases (LIFE), Leipzig University, Leipzig, Germany.

出版信息

Ophthalmic Physiol Opt. 2021 May;41(3):512-522. doi: 10.1111/opo.12807. Epub 2021 Mar 27.

Abstract

PURPOSE

To evaluate the feasibility and repeatability of Lenstar LS 900 biometry measurements in a paediatric population.

METHODS

Children were examined as part of the LIFE Child Study (Leipzig Research Centre for Civilization Diseases), a population-based study in Leipzig, Germany. Altogether, 1917 children, aged from 3.5 to 17.5 years, were assessed with the Haag Streit Lenstar LS 900. Three consecutive measurements of the right eye were analysed for axial length, central corneal thickness, anterior chamber depth, aqueous depth, lens thickness and flat and steep corneal radii. The number of successful measurements and repeatability were evaluated for each parameter and three age bands (3.5 to 6.5 years, 6.5 to 10.5 years and 10.5 to 17.5 years).

RESULTS

Best measurement feasibility was found for axial length and central corneal thickness (91% to 100%), followed by flat and steep corneal radii (86% to 100%), anterior chamber and aqueous depth (76% to 92%) and lens thickness (50% to 81%), with higher numbers for older children. Repeatability values (in mm) were: axial length 0.025 to 0.035; central corneal thickness 0.003 to 0.027; aqueous depth 0.024 to 0.058; anterior chamber 0.024 to 0.054; lens thickness 0.034 to 0.067. An overall trend showed better repeatability for older children, especially for central corneal thickness, aqueous depth and lens thickness.

CONCLUSIONS

For ocular biometry in the paediatric population, axial length, central corneal thickness, flat and steep corneal radii can be measured very reliably even in children from 4 years old onward using the Lenstar LS 900. Lens thickness can be quantified in a limited number of younger children. Repeatability was high for all variables investigated. Repeatability improved with age, reaching adult values in the adolescent age band. Established repeatability limits can be applied in future studies as a quality parameter.

摘要

目的

评估 Lenstar LS 900 生物测量仪在儿科人群中的可行性和可重复性。

方法

作为德国莱比锡生命儿童研究(Leipzig Research Centre for Civilization Diseases)的一部分,对儿童进行了检查。共有 1917 名年龄在 3.5 至 17.5 岁的儿童接受了 Haag Streit Lenstar LS 900 的检查。对右眼进行了 3 次连续测量,以评估眼轴长度、中央角膜厚度、前房深度、房水深度、晶状体厚度以及平角膜和陡角膜半径。评估了每个参数的成功测量次数和可重复性,并分为三个年龄组(3.5 至 6.5 岁、6.5 至 10.5 岁和 10.5 至 17.5 岁)。

结果

最佳测量可行性发现是眼轴长度和中央角膜厚度(91%至 100%),其次是平角膜和陡角膜半径(86%至 100%)、前房和房水深度(76%至 92%)和晶状体厚度(50%至 81%),年龄较大的儿童数量更高。重复性值(以毫米为单位)为:眼轴长度 0.025 至 0.035;中央角膜厚度 0.003 至 0.027;房水深度 0.024 至 0.058;前房 0.024 至 0.054;晶状体厚度 0.034 至 0.067。总体趋势表明,年龄较大的儿童,尤其是中央角膜厚度、房水深度和晶状体厚度的可重复性更好。

结论

对于儿科人群的眼部生物测量,即使是 4 岁以上的儿童,Lenstar LS 900 也可以非常可靠地测量眼轴长度、中央角膜厚度、平角膜和陡角膜半径。晶状体厚度可以在少数年龄较小的儿童中进行定量评估。所有研究变量的重复性均较高。随着年龄的增长,重复性提高,在青少年年龄组达到成人水平。未来的研究可以将既定的重复性限值作为质量参数。

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