Department of Software, Korea National University of Transportation, Chungju, 27469, South Korea.
Department of Computer Science and Engineering, Seoul National University, Seoul, 08826, South Korea.
Sci Rep. 2023 Jun 5;13(1):9087. doi: 10.1038/s41598-023-36311-0.
Diabetic retinopathy (DR) is a diabetes complication that can cause vision loss among patients due to damage to blood vessels in the retina. Early retinal screening can avoid the severe consequences of DR and enable timely treatment. Nowadays, researchers are trying to develop automated deep learning-based DR segmentation tools using retinal fundus images to help Ophthalmologists with DR screening and early diagnosis. However, recent studies are unable to design accurate models due to the unavailability of larger training data with consistent and fine-grained annotations. To address this problem, we propose a semi-supervised multitask learning approach that exploits widely available unlabelled data (i.e., Kaggle-EyePACS) to improve DR segmentation performance. The proposed model consists of novel multi-decoder architecture and involves both unsupervised and supervised learning phases. The model is trained for the unsupervised auxiliary task to effectively learn from additional unlabelled data and improve the performance of the primary task of DR segmentation. The proposed technique is rigorously evaluated on two publicly available datasets (i.e., FGADR and IDRiD) and results show that the proposed technique not only outperforms existing state-of-the-art techniques but also exhibits improved generalisation and robustness for cross-data evaluation.
糖尿病性视网膜病变 (DR) 是一种糖尿病并发症,可导致视网膜血管损伤,使患者视力丧失。早期视网膜筛查可以避免 DR 的严重后果,并能及时进行治疗。如今,研究人员正试图开发基于深度学习的自动化 DR 分割工具,利用眼底图像来帮助眼科医生进行 DR 筛查和早期诊断。然而,由于缺乏具有一致和精细注释的更大训练数据,最近的研究无法设计出准确的模型。为了解决这个问题,我们提出了一种半监督多任务学习方法,利用广泛可用的未标记数据(即 Kaggle-EyePACS)来提高 DR 分割性能。所提出的模型由新颖的多解码器架构组成,涉及无监督和监督学习阶段。该模型经过无监督辅助任务的训练,可有效从额外的未标记数据中学习,并提高 DR 分割的主要任务性能。所提出的技术在两个公开可用的数据集(即 FGADR 和 IDRiD)上进行了严格评估,结果表明,所提出的技术不仅优于现有的最先进技术,而且还表现出了改进的泛化能力和跨数据评估的稳健性。