Department of Anaesthesiology, Kolding Hospital, a part of Lillebaelt Hospital, University Hospital of Southern Denmark, Denmark.
Department of Anaesthesiology, Vejle Hospital, a part of Lillebaelt Hospital, University Hospital of Southern Denmark, Denmark.
Acta Anaesthesiol Scand. 2023 Oct;67(9):1266-1272. doi: 10.1111/aas.14289. Epub 2023 Jun 6.
Major ankle and hindfoot surgery (e.g., ankle, triple and subtalar arthrodesis) typically causes severe postoperative pain, especially the first two postoperative days. Current modalities of postoperative analgesic treatment often include continuous peripheral nerve blocks of the saphenous and sciatic nerves via catheters in order to extend the duration of pain- and opioid-free nerve blockade to 48 h. Unfortunately, the 48 h-efficacy of continuous infusion via a catheter is reduced by a high displacement rate. We hypothesised that one-time repetition of the single injection peripheral nerve blocks would provide effective analgesia with a low opioid consumption the first 48 postoperative hours.
Eleven subjects preoperatively received a popliteal sciatic and a saphenous single injection nerve block with a protracted local anaesthetic mixture. Surgery was performed under general anaesthesia. The one-time repetition of the single injection nerve block was carried out approximately 24 h after the primary nerve block. The main outcomes were pain and cumulative opioid consumption during the first 48 postoperative hours.
Nine of the 11 (82%) patients had effective analgesia without opioids during the first 48 postoperative hours. Two patients each required a single dose of 7.5 mg of oral morphine equivalents after 43 h.
One-time repetition of single injection saphenous and sciatic nerve blocks consistently provided effective analgesia practically without opioids for 48 h after major elective ankle and hindfoot surgery.
大踝关节和后足手术(例如,踝关节、三关节和距下关节融合术)通常会导致严重的术后疼痛,尤其是术后前两天。目前的术后镇痛治疗方法通常包括通过导管对隐神经和坐骨神经进行连续外周神经阻滞,以将疼痛和无阿片类药物神经阻滞的持续时间延长至 48 小时。不幸的是,导管持续输注的 48 小时疗效因高移位率而降低。我们假设单次重复单次注射外周神经阻滞将在术后 48 小时内提供有效的镇痛作用,并减少阿片类药物的消耗。
11 名受试者在术前接受了隐神经和坐骨神经单次注射神经阻滞,并使用延长局部麻醉混合物。手术在全身麻醉下进行。大约在初次神经阻滞后 24 小时进行单次重复神经阻滞。主要结果是术后 48 小时内的疼痛和累积阿片类药物消耗量。
9 名(82%)患者在术后 48 小时内无需阿片类药物即可有效镇痛。2 名患者在 43 小时后各需要口服吗啡等效物 7.5mg。
在大选择性踝关节和后足手术后,单次重复隐神经和坐骨神经阻滞可在 48 小时内持续有效地提供镇痛作用,且几乎无需使用阿片类药物。