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人工智能与青光眼:回归基础

Artificial Intelligence and Glaucoma: Going Back to Basics.

作者信息

AlRyalat Saif Aldeen, Singh Praveer, Kalpathy-Cramer Jayashree, Kahook Malik Y

机构信息

Department of Ophthalmology, The University of Jordan, Amman, 11942, Jordan.

Department of Ophthalmology, University of Colorado School of Medicine, Sue Anschutz-Rodgers Eye Center, Aurora, CO, USA.

出版信息

Clin Ophthalmol. 2023 May 31;17:1525-1530. doi: 10.2147/OPTH.S410905. eCollection 2023.

DOI:10.2147/OPTH.S410905
PMID:37284059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10239633/
Abstract

There has been a recent surge in the number of publications centered on the use of artificial intelligence (AI) to diagnose various systemic diseases. The Food and Drug Administration has approved several algorithms for use in clinical practice. In ophthalmology, most advances in AI relate to diabetic retinopathy, which is a disease process with agreed upon diagnostic and classification criteria. However, this is not the case for glaucoma, which is a relatively complex disease without agreed-upon diagnostic criteria. Moreover, currently available public datasets that focus on glaucoma have inconstant label quality, further complicating attempts at training AI algorithms efficiently. In this perspective paper, we discuss specific details related to developing AI models for glaucoma and suggest potential steps to overcome current limitations.

摘要

最近,以使用人工智能(AI)诊断各种全身性疾病为中心的出版物数量激增。美国食品药品监督管理局已批准了几种算法用于临床实践。在眼科领域,AI的大多数进展都与糖尿病视网膜病变有关,这是一种具有公认诊断和分类标准的疾病过程。然而,青光眼并非如此,青光眼是一种相对复杂的疾病,没有公认的诊断标准。此外,目前可用的专注于青光眼的公共数据集的标签质量不稳定,这使得有效训练AI算法的尝试更加复杂。在这篇观点论文中,我们讨论了与开发青光眼AI模型相关的具体细节,并提出了克服当前局限性的潜在步骤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea41/10239633/2f10e5cbcd5d/OPTH-17-1525-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea41/10239633/4123f8828d2c/OPTH-17-1525-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea41/10239633/2f10e5cbcd5d/OPTH-17-1525-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea41/10239633/4123f8828d2c/OPTH-17-1525-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea41/10239633/2f10e5cbcd5d/OPTH-17-1525-g0002.jpg

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Front Ophthalmol (Lausanne). 2024 Jun 7;4:1387190. doi: 10.3389/fopht.2024.1387190. eCollection 2024.
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本文引用的文献

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Multimodal biomedical AI.多模态生物医学人工智能。
Nat Med. 2022 Sep;28(9):1773-1784. doi: 10.1038/s41591-022-01981-2. Epub 2022 Sep 15.
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External Validation of a Retinopathy of Prematurity Screening Model Using Artificial Intelligence in 3 Low- and Middle-Income Populations.人工智能在 3 个中低收入人群中对早产儿视网膜病变筛查模型的外部验证。
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Diagnostic Accuracy of Artificial Intelligence in Glaucoma Screening and Clinical Practice.人工智能在青光眼筛查及临床实践中的诊断准确性
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Defining and diagnosing glaucoma: a focus on blindness prevention.青光眼的定义与诊断:聚焦于预防失明
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Deep Learning Prediction of Response to Anti-VEGF among Diabetic Macular Edema Patients: Treatment Response Analyzer System (TRAS).糖尿病性黄斑水肿患者抗VEGF治疗反应的深度学习预测:治疗反应分析系统(TRAS)
Diagnostics (Basel). 2022 Jan 26;12(2):312. doi: 10.3390/diagnostics12020312.
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Designs and Methodologies Used in Landmark Clinical Trials of Glaucoma: Implications for Future Big Data Mining and Actionable Disease Treatment.青光眼标志性临床试验中使用的设计与方法:对未来大数据挖掘及可实施疾病治疗的启示
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Multimodal Machine Learning Using Visual Fields and Peripapillary Circular OCT Scans in Detection of Glaucomatous Optic Neuropathy.基于视野和视盘周围环形 OCT 扫描的多模态机器学习在青光眼视神经病变检测中的应用。
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