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儿童猴痘管理的临床与流行病学干预措施:一项系统评价

Clinical and Epidemiological Interventions for Monkeypox Management in Children: A Systematic Review.

作者信息

Maru Viral, Ghaffar Usama Bin, Rawat Anurag, Yunus Mohammed, Langaliya Akshayraj K, Vyas Shubhangi, Mehta Dhaval, Ojha Akshaya

机构信息

Pediatric Dentistry, Government Dental College and Hospital, Mumbai, IND.

Basic Sciences, Majmaah University, Al Majmaah, SAU.

出版信息

Cureus. 2023 May 4;15(5):e38521. doi: 10.7759/cureus.38521. eCollection 2023 May.

DOI:10.7759/cureus.38521
PMID:37288174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10241661/
Abstract

This review aims to compile the available literature on monkeypox, identify risk factors for developing the disease, and recommend effective preventative methods to reduce the number of reported cases and fatalities in children and pregnant women. In seeking out pertinent studies on monkeypox virus in children and pregnant women, we searched the literature using the databases Cochrane Library, Google Scholar, PubMed, EMBASE, Web of Science, and Scopus up to 1st February 2023. This study analyzed data from case studies of monkeypox in children and pregnant women. Clinical data and test findings of monkeypox patients less than 18 years old and pregnant women were analyzed. The Newcastle-Ottawa Scale was used to do the quality evaluation. Our record examination spanned the years 1985 to 2023 and found 17 children and five pregnant female patients treated with monkeypox in various hospitals/community centers. Zaire, Gabon, Chicago, Sierra Leone, Central African Republic, Northern DR Congo, Liberia, Cameroon, the Democratic Republic of the Congo, the United Kingdom, the Netherlands, and Florida all contributed to the 14 studies analyzed. There were no studies identified for meta-analysis of selected case studies of hospitalized children and pregnant women who were diagnosed with monkeypox. The incidence, prevalence, clinical characteristics, diagnosis, management, prevention, vaccinations, infant care, and care for expectant mothers are all discussed in this systematic review of monkeypox in children. Our research findings may provide a foundation for further focused research and the development of related recommendations or guidelines.

摘要

本综述旨在汇编有关猴痘的现有文献,确定该疾病的危险因素,并推荐有效的预防方法,以减少儿童和孕妇中报告的病例数和死亡人数。在寻找有关儿童和孕妇猴痘病毒的相关研究时,我们使用Cochrane图书馆、谷歌学术、PubMed、EMBASE、科学网和Scopus数据库检索了截至2023年2月1日的文献。本研究分析了儿童和孕妇猴痘病例研究的数据。分析了18岁以下猴痘患者和孕妇的临床数据及检测结果。采用纽卡斯尔-渥太华量表进行质量评估。我们的文献检索跨度为1985年至2023年,发现17名儿童和5名孕妇在不同医院/社区中心接受了猴痘治疗。扎伊尔、加蓬、芝加哥、塞拉利昂、中非共和国、刚果民主共和国北部、利比里亚、喀麦隆、刚果民主共和国、英国、荷兰和佛罗里达州都为所分析的14项研究提供了数据。未发现对确诊为猴痘的住院儿童和孕妇的选定病例研究进行荟萃分析的研究。本儿童猴痘系统综述讨论了发病率、患病率、临床特征、诊断、管理、预防、疫苗接种、婴儿护理和对孕妇的护理。我们的研究结果可能为进一步的针对性研究以及相关建议或指南的制定提供基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a3/10241661/7ba4c68faf07/cureus-0015-00000038521-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a3/10241661/7ba4c68faf07/cureus-0015-00000038521-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83a3/10241661/7ba4c68faf07/cureus-0015-00000038521-i01.jpg

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本文引用的文献

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Clinical Conundrums: Differentiating Monkeypox From Similarly Presenting Infections.临床难题:猴痘与表现相似的感染的鉴别诊断
Cureus. 2022 Oct 4;14(10):e29929. doi: 10.7759/cureus.29929. eCollection 2022 Oct.
2
Clinical manifestations of human monkeypox infection and implications for outbreak strategy.人类猴痘感染的临床表现及其对疫情应对策略的影响。
Health Sci Rev (Oxf). 2022 Dec;5:100055. doi: 10.1016/j.hsr.2022.100055. Epub 2022 Oct 6.
3
Emergence and dissemination of monkeypox, an intimidating global public health problem.
猴痘的出现和传播是一个令人担忧的全球公共卫生问题。
J Infect Public Health. 2022 Oct;15(10):1156-1165. doi: 10.1016/j.jiph.2022.09.008. Epub 2022 Sep 24.
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Monkeypox in a Young Infant - Florida, 2022.2022 年佛罗里达州一名婴儿感染猴痘病毒。
MMWR Morb Mortal Wkly Rep. 2022 Sep 23;71(38):1220-1221. doi: 10.15585/mmwr.mm7138e3.
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A case report of monkeypox as a result of conflict in the context of a measles campaign.在麻疹疫苗接种活动背景下因冲突导致猴痘的病例报告。
Public Health Pract (Oxf). 2022 Sep 12;4:100312. doi: 10.1016/j.puhip.2022.100312. eCollection 2022 Dec.
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Monkeypox: A Brief for Perinatal Nurses.猴痘:围产期护士简报。
MCN Am J Matern Child Nurs. 2023;48(1):48. doi: 10.1097/NMC.0000000000000878.
7
Preparedness of Eastern Mediterranean countries in view of monkeypox emergence during the COVID-19 pandemic: A call for action.东地中海国家在新冠疫情期间应对猴痘出现的准备情况:行动呼吁。
Int J Surg. 2022 Sep;105:106878. doi: 10.1016/j.ijsu.2022.106878. Epub 2022 Sep 5.
8
Risks of monkeypox virus infection in children.儿童感染猴痘病毒的风险。
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