氨曲南在腹部组织和胆汁中的浓度。
Aztreonam concentration in abdominal tissues and bile.
作者信息
Condon R E, Friedhoff L T, Edmiston C E, Levinson B
出版信息
Antimicrob Agents Chemother. 1986 Jun;29(6):1101-3. doi: 10.1128/AAC.29.6.1101.
Abstract
Abdominal tissue, serum, and bile samples were obtained from 37 patients given a single, 2-g intravenous infusion of aztreonam immediately prior to an elective abdominal operation. Samples were obtained at 0 to 6 h after dosing. Mean concentrations in tissues and fluids and specimen/serum rations are reported. Levels in tissue and bile exceeded the reported MICs for 90% of most members of the family Enterobacteriaceae for up to 6 h.
摘要
在37例择期腹部手术前立即接受单次2克静脉注射氨曲南的患者中获取腹部组织、血清和胆汁样本。给药后0至6小时采集样本。报告了组织和体液中的平均浓度以及标本/血清比率。组织和胆汁中的浓度在长达6小时内超过了肠杆菌科大多数成员报告的90%的最低抑菌浓度。
相似文献
1
Aztreonam concentration in abdominal tissues and bile.氨曲南在腹部组织和胆汁中的浓度。
Antimicrob Agents Chemother. 1986 Jun;29(6):1101-3. doi: 10.1128/AAC.29.6.1101.
2
Aztreonam concentrations in human tissues obtained during thoracic and gynecologic surgery.在胸外科和妇科手术期间获取的人体组织中的氨曲南浓度。
Antimicrob Agents Chemother. 1986 Sep;30(3):505-7. doi: 10.1128/AAC.30.3.505.
3
Pharmacokinetics and extravascular penetration of aztreonam in patients with abdominal sepsis.
Rev Infect Dis. 1985 Nov-Dec;7 Suppl 4:S716-23. doi: 10.1093/clinids/7.supplement_4.s716.
4
Comparative pharmacokinetics of carumonam and aztreonam in mice, rats, rabbits, dogs, and cynomolgus monkeys.卡芦莫南和氨曲南在小鼠、大鼠、家兔、犬及食蟹猴体内的比较药代动力学。
Antimicrob Agents Chemother. 1986 Jan;29(1):127-34. doi: 10.1128/AAC.29.1.127.
5
Aztreonam penetration into synovial fluid and bone.氨曲南在滑液和骨中的渗透情况。
Antimicrob Agents Chemother. 1986 Apr;29(4):710-2. doi: 10.1128/AAC.29.4.710.
6
Aztreonam concentrations in human prostatic tissue.氨曲南在人体前列腺组织中的浓度。
Antimicrob Agents Chemother. 1984 Jul;26(1):20-1. doi: 10.1128/AAC.26.1.20.
7
[Study on transfer of aztreonam into female genital organs].
Jpn J Antibiot. 1985 Dec;38(12):3666-73.
8
[Aztreonam. Diffusion into bronchial mucus].
Pathol Biol (Paris). 1985 Jun;33(5 Pt 2):533-7.
9
Pharmacology of aztreonam after intravenous infusion.静脉输注后氨曲南的药理学。
Antimicrob Agents Chemother. 1983 Jul;24(1):18-22. doi: 10.1128/AAC.24.1.18.
10
Clinical-experimental research on aztreonam ampullar and ureteral concentrations.
Chemioterapia. 1987 Apr;6(2):124-8.
本文引用的文献
1
Concentrations of cefamandole and cefsulodin in serum, heart valves, subcutaneous tissue, and muscle of patients undergoing open-heart surgery.接受心脏直视手术患者血清、心脏瓣膜、皮下组织及肌肉中头孢孟多和头孢磺啶的浓度。
J Infect Dis. 1980 Aug;142(2):290. doi: 10.1093/infdis/142.2.290.
2
Single-dose pharmacokinetics of the monobactam azthreonam (SQ 26,776) in healthy subjects.健康受试者中单环β-内酰胺类氨曲南（SQ 26,776）的单剂量药代动力学。
Antimicrob Agents Chemother. 1982 Jun;21(6):944-9. doi: 10.1128/AAC.21.6.944.
3
Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria.氨曲南（SQ 26,776），一种对需氧革兰氏阴性菌有特效的合成单环β-内酰胺抗生素。
Antimicrob Agents Chemother. 1982 Jan;21(1):85-92. doi: 10.1128/AAC.21.1.85.
4
High-pressure liquid chromatographic analysis of aztreonam in sera and urine.血清和尿液中氨曲南的高效液相色谱分析
Antimicrob Agents Chemother. 1983 Jun;23(6):852-6. doi: 10.1128/AAC.23.6.852.
5
In vitro activities of aztreonam, piperacillin, and ticarcillin combined with amikacin against amikacin-resistant Pseudomonas aeruginosa and P. cepacia isolates from children with cystic fibrosis.氨曲南、哌拉西林和替卡西林联合阿米卡星对来自囊性纤维化患儿的耐阿米卡星铜绿假单胞菌和洋葱伯克霍尔德菌分离株的体外活性。
Antimicrob Agents Chemother. 1984 Feb;25(2):279-80. doi: 10.1128/AAC.25.2.279.
6
Biliary excretion of aztreonam in patients with biliary tract disease.氨曲南在胆道疾病患者中的胆汁排泄情况。
Antimicrob Agents Chemother. 1984 Mar;25(3):358-61. doi: 10.1128/AAC.25.3.358.
7
In vitro activity of aztreonam in combination with newer beta-lactams and amikacin against multiply resistant gram-negative bacilli.氨曲南与新型β-内酰胺类抗生素及阿米卡星联合应用对多重耐药革兰阴性杆菌的体外活性
Antimicrob Agents Chemother. 1984 Feb;25(2):283-5. doi: 10.1128/AAC.25.2.283.
8
Serum bactericidal activity of aztreonam, cefoperazone, and amikacin, alone or in combination, against Escherichia coli, Klebsiella pneumoniae, Serratia marcescens, and Pseudomonas aeruginosa.氨曲南、头孢哌酮和阿米卡星单独或联合使用对大肠杆菌、肺炎克雷伯菌、粘质沙雷氏菌和铜绿假单胞菌的血清杀菌活性。
Antimicrob Agents Chemother. 1984 Aug;26(2):224-7. doi: 10.1128/AAC.26.2.224.
9
Aztreonam concentrations in human prostatic tissue.氨曲南在人体前列腺组织中的浓度。
Antimicrob Agents Chemother. 1984 Jul;26(1):20-1. doi: 10.1128/AAC.26.1.20.
10
The excretion of antibiotics by the biliary tract.抗生素经胆道的排泄。
Surg Gynecol Obstet. 1984 Jun;158(6):601-7.
Zotero 插件