Fields S D, MacKenzie C R, Charlson M E, Perry S W
Arch Intern Med. 1986 Aug;146(8):1593-6.
To determine outcomes of patients admitted to the hospital with global cognitive impairment and to identify factors that might predict improvement, we screened all medical ward admissions over a one-month period with Folstein's Mini-Mental State Examination. Of 115 patients, 23 (20%) scored less than 24, indicating that they were cognitively impaired. Nineteen patients survived to discharge and were followed up for three months; three additional patients died in this period. Nine (47%) of the 19 patients significantly improved their Mini-Mental State scores. Five (26%) of the 19 improved to normal. They scored better on the initial Mini-Mental State Examination and lower (less dementia) on Blessed's Dementia Rating Scale. Age, severity and stability of medical illness, presence of neurologic abnormalities, clinical course, extensiveness of medical evaluation, and psychiatric criteria for delirium did not predict improvement.
为了确定因全球认知障碍入院患者的治疗结果，并找出可能预测病情改善的因素，我们在一个月的时间里，使用福尔斯坦简易精神状态检查表对所有内科病房的入院患者进行了筛查。在115名患者中，23名（20%）得分低于24分，表明他们存在认知障碍。19名患者存活至出院，并接受了为期三个月的随访；在此期间又有3名患者死亡。19名患者中有9名（47%）的简易精神状态检查表得分显著提高。19名患者中有5名（26%）恢复正常。他们在最初的简易精神状态检查表上得分更高，在布列斯痴呆评定量表上得分更低（痴呆程度较轻）。年龄、内科疾病的严重程度和稳定性、神经系统异常的存在、临床病程、医学评估的全面性以及谵妄的精神科标准均不能预测病情改善情况。
