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种子油——富含不饱和脂肪酸和具有DNA保护潜力的植物化合物的天然来源。

Seed Oil-A Rich Natural Source of Unsaturated Fatty Acids and Phytocompounds with DNA Protective Potential.

作者信息

Andonova Tsvetelina, Muhovski Yordan, Apostolova Elena, Naimov Samir, Petkova Zhana, Teneva Olga, Antova Ginka, Slavov Iliya, Dimitrova-Dyulgerova Ivanka

机构信息

Department of Botany and Biological Education, Faculty of Biology, University of Plovdiv "Paisii Hilendarski", 24 Tzar Asen Street, 4000 Plovdiv, Bulgaria.

Life Sciences Department, Walloon Agricultural Research Centre, 5030 Gembloux, Belgium.

出版信息

Foods. 2023 Jun 1;12(11):2230. doi: 10.3390/foods12112230.

Abstract

The present work is focused on the physicochemical characteristics, chemical composition, and some biological activities of seed oil. The glyceride oil, obtained with a Soxhlet apparatus by extraction with hexane, was characterized by a relatively high oil content (over 20%), and it is defined as a non-drying oil (iodine value-44 gI/100 g) with good oxidative stability (over 50 h). There were identified 11 fatty acids, 6 sterols, 3 tocopherols, and 6 phospholipids, as the last group was reported for the first time. The major components among them were-monounsaturated eicosenoic and oleic acids, -sitosterol, -tocopherol, and phosphatidylcholine. The in vitro tests demonstrated DNA protective activity and a lack of cytotoxicity of the oil, data that has been reported for the first time. The in vitro MTT test of the oil on HT-29 and PC3 cell lines did not indicate antitumor activity. The seed oil studied contains valuable bio-components, which have proven benefits for human health, and that is why it could be used in food, cosmetic, and pharmaceutical products.

摘要

本研究聚焦于种子油的物理化学特性、化学成分及一些生物活性。通过索氏提取器用己烷提取得到的甘油酯油,其特点是含油率相对较高(超过20%),被定义为具有良好氧化稳定性(超过50小时)的不干性油(碘值为44 gI/100 g)。已鉴定出11种脂肪酸、6种甾醇、3种生育酚和6种磷脂,其中最后一组是首次报道。它们当中的主要成分是单不饱和的二十碳烯酸和油酸、β-谷甾醇、γ-生育酚和磷脂酰胆碱。体外试验表明该油具有DNA保护活性且无细胞毒性,这些数据是首次报道。该油对HT - 29和PC3细胞系的体外MTT试验未显示出抗肿瘤活性。所研究的种子油含有对人体健康有益的有价值生物成分,这就是它可用于食品、化妆品和药品的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a6a/10252210/732470ee4816/foods-12-02230-g001.jpg

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