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引用本文的文献

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Infant Non-Secretor Histoblood Group Antigen Phenotype Reduces Susceptibility to Both Symptomatic and Asymptomatic Rotavirus Infection.婴儿非分泌型组织血型抗原表型降低了有症状和无症状轮状病毒感染的易感性。
Pathogens. 2024 Mar 4;13(3):223. doi: 10.3390/pathogens13030223.

本文引用的文献

1
Effect of Infant and Maternal Secretor Status on Rotavirus Vaccine Take-An Overview.婴儿和产妇分泌状态对轮状病毒疫苗效果的影响：概述。
Viruses. 2021 Jun 14;13(6):1144. doi: 10.3390/v13061144.
2
Update on rotavirus vaccine underperformance in low- to middle-income countries and next-generation vaccines.轮状病毒疫苗在中低收入国家表现不佳的最新情况和下一代疫苗。
Hum Vaccin Immunother. 2021 Jun 3;17(6):1787-1802. doi: 10.1080/21645515.2020.1844525. Epub 2020 Dec 17.
3
Maternal Secretor Status Affects Oral Rotavirus Vaccine Response in Breastfed Infants in Bangladesh.母婴分泌型状态影响孟加拉国母乳喂养婴儿口服轮状病毒疫苗的反应。
J Infect Dis. 2021 Oct 13;224(7):1147-1151. doi: 10.1093/infdis/jiaa101.
4
Effects of Child and Maternal Histo-Blood Group Antigen Status on Symptomatic and Asymptomatic Enteric Infections in Early Childhood.母婴组织相容性血型抗原状态对婴幼儿期症状性和无症状性肠内感染的影响。
J Infect Dis. 2019 Jun 5;220(1):151-162. doi: 10.1093/infdis/jiz072.
5
Use of quantitative molecular diagnostic methods to assess the aetiology, burden, and clinical characteristics of diarrhoea in children in low-resource settings: a reanalysis of the MAL-ED cohort study.采用定量分子诊断方法评估资源匮乏环境下儿童腹泻的病因、负担和临床特征： MAL-ED 队列研究的再分析。
Lancet Glob Health. 2018 Dec;6(12):e1309-e1318. doi: 10.1016/S2214-109X(18)30349-8. Epub 2018 Oct 1.
6
Quantifying the Impact of Natural Immunity on Rotavirus Vaccine Efficacy Estimates: A Clinical Trial in Dhaka, Bangladesh (PROVIDE) and a Simulation Study.量化自然免疫对轮状病毒疫苗效力估计的影响：孟加拉国达卡的一项临床试验（PROVIDE）和一项模拟研究。
J Infect Dis. 2018 Mar 5;217(6):861-868. doi: 10.1093/infdis/jix668.
7
Rotavirus-Specific Immunoglobulin A Responses Are Impaired and Serve as a Suboptimal Correlate of Protection Among Infants in Bangladesh.轮状病毒特异性免疫球蛋白 A 反应受损，且作为孟加拉国婴儿保护效果的次优相关因素。
Clin Infect Dis. 2018 Jul 2;67(2):186-192. doi: 10.1093/cid/ciy076.
8
Histo-Blood Group Antigen Phenotype Determines Susceptibility to Genotype-Specific Rotavirus Infections and Impacts Measures of Rotavirus Vaccine Efficacy.组织血型抗原表型决定对基因型特异性轮状病毒感染的易感性，并影响轮状病毒疫苗效力的衡量标准。
J Infect Dis. 2018 Apr 11;217(9):1399-1407. doi: 10.1093/infdis/jiy054.
9
Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study.运用定量分子诊断方法确定儿童腹泻病因：全球儿童急性腹泻病监测研究病例对照研究的重新分析
Lancet. 2016 Sep 24;388(10051):1291-301. doi: 10.1016/S0140-6736(16)31529-X.
10
Delayed Dosing of Oral Rotavirus Vaccine Demonstrates Decreased Risk of Rotavirus Gastroenteritis Associated With Serum Zinc: A Randomized Controlled Trial.口服轮状病毒疫苗延迟接种可降低血清锌相关轮状病毒胃肠炎风险：一项随机对照试验。
Clin Infect Dis. 2016 Sep 1;63(5):634-41. doi: 10.1093/cid/ciw346. Epub 2016 May 23.

母亲的母乳分泌型表型不影响婴儿对轮状病毒腹泻的易感性。

Maternal Breast Milk Secretor Phenotype Does Not Affect Infant Susceptibility to Rotavirus Diarrhea.

作者信息

Williams Frank B, Kader Md Abdul, Dickson Dorothy M, Colgate E Ross, Alam Masud, Haque Rashidul, Petri William A, Kirkpatrick Beth D, Lee Benjamin

机构信息

Vaccine Testing Center and Translational Global Infectious Diseases Research Center, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.

International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.

出版信息

Open Forum Infect Dis. 2023 Jun 7;10(6):ofad299. doi: 10.1093/ofid/ofad299. eCollection 2023 Jun.

DOI:10.1093/ofid/ofad299
PMID:37333724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10270652/
Abstract

Breast milk secretor status is associated with antibody seroconversion to oral rotavirus vaccination. Here, we were unable to detect a similar impact on risk of infant rotavirus diarrhea or vaccine efficacy through 2 years of life, underscoring limitations of immunogenicity assessment alone in evaluation of oral rotavirus vaccine response.

摘要

母乳分泌状态与口服轮状病毒疫苗后的抗体血清转化有关。在此，我们未能检测到对2岁以内婴儿轮状病毒腹泻风险或疫苗效力有类似影响，这突出了仅通过免疫原性评估来评价口服轮状病毒疫苗反应的局限性。