文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

穿山甲启发的非束缚磁性机器人,用于按需生物医学加热应用。

Pangolin-inspired untethered magnetic robot for on-demand biomedical heating applications.

机构信息

Physical Intelligence Department, Max Planck Institute for Intelligent Systems, 70569, Stuttgart, Germany.

Institute for Biomedical Engineering, ETH Zürich, 8092, Zürich, Switzerland.

出版信息

Nat Commun. 2023 Jun 20;14(1):3320. doi: 10.1038/s41467-023-38689-x.


DOI:10.1038/s41467-023-38689-x
PMID:37339969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10282021/
Abstract

Untethered magnetic miniature soft robots capable of accessing hard-to-reach regions can enable safe, disruptive, and minimally invasive medical procedures. However, the soft body limits the integration of non-magnetic external stimuli sources on the robot, thereby restricting the functionalities of such robots. One such functionality is localised heat generation, which requires solid metallic materials for increased efficiency. Yet, using these materials compromises the compliance and safety of using soft robots. To overcome these competing requirements, we propose a pangolin-inspired bi-layered soft robot design. We show that the reported design achieves heating > 70 °C at large distances > 5 cm within a short period of time <30 s, allowing users to realise on-demand localised heating in tandem with shape-morphing capabilities. We demonstrate advanced robotic functionalities, such as selective cargo release, in situ demagnetisation, hyperthermia and mitigation of bleeding, on tissue phantoms and ex vivo tissues.

摘要

无束缚的磁性微型软体机器人能够进入难以到达的区域,可以实现安全、颠覆性和微创的医疗程序。然而,软体身体限制了非磁性外部刺激源在机器人上的集成,从而限制了此类机器人的功能。其中一个功能是局部发热,这需要使用固体金属材料来提高效率。然而,使用这些材料会影响使用软体机器人的顺应性和安全性。为了克服这些相互竞争的需求,我们提出了一种穿山甲启发的双层软体机器人设计。我们表明,所报道的设计在短时间内<30 秒内,在>5 厘米的大距离处实现了>70°C 的加热,允许用户与形状变形能力一起实现按需局部加热。我们在组织模型和离体组织上展示了高级机器人功能,如选择性货物释放、原位去磁、高热和止血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/078aa8ce7c14/41467_2023_38689_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/4dee0018e4e3/41467_2023_38689_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/d8c82c190e82/41467_2023_38689_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/bbd5b32baa21/41467_2023_38689_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/c166024018e9/41467_2023_38689_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/1ad557b9235b/41467_2023_38689_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/4a8b8df22930/41467_2023_38689_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/078aa8ce7c14/41467_2023_38689_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/4dee0018e4e3/41467_2023_38689_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/d8c82c190e82/41467_2023_38689_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/bbd5b32baa21/41467_2023_38689_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/c166024018e9/41467_2023_38689_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/1ad557b9235b/41467_2023_38689_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/4a8b8df22930/41467_2023_38689_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1781/10282021/078aa8ce7c14/41467_2023_38689_Fig7_HTML.jpg

相似文献

[1]
Pangolin-inspired untethered magnetic robot for on-demand biomedical heating applications.

Nat Commun. 2023-6-20

[2]
On-demand anchoring of wireless soft miniature robots on soft surfaces.

Proc Natl Acad Sci U S A. 2022-8-23

[3]
Liquid Metal-Elastomer Composites with Dual-Energy Transmission Mode for Multifunctional Miniature Untethered Magnetic Robots.

Adv Sci (Weinh). 2022-11

[4]
Untethered Miniature Tensegrity Robot with Tunable Stiffness for High-Speed and Adaptive Locomotion.

Soft Robot. 2025-4-15

[5]
Design of a Bio-Inspired Untethered Soft Octopodal Robot Driven by Magnetic Field.

Biomimetics (Basel). 2023-6-22

[6]
Focused ultrasound enables selective actuation and Newton-level force output of untethered soft robots.

Nat Commun. 2024-6-18

[7]
Single-step precision programming of decoupled multiresponsive soft millirobots.

Proc Natl Acad Sci U S A. 2024-3-26

[8]
A magnetic multi-layer soft robot for on-demand targeted adhesion.

Nat Commun. 2024-1-20

[9]
Crawling, climbing, perching, and flying by FiBa soft robots.

Sci Robot. 2024-7-17

[10]
Biodegradable Magnetic Hydrogel Robot with Multimodal Locomotion for Targeted Cargo Delivery.

ACS Appl Mater Interfaces. 2023-6-21

引用本文的文献

[1]
A Multimodal Amphibious Robot Driven by Soft Electrohydraulic Flippers.

Cyborg Bionic Syst. 2025-6-9

[2]
The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots.

Adv Sci (Weinh). 2025-8

[3]
A Multifunctional Capsule-like Puncture Biopsy Robot for the Gastrointestinal System.

Micromachines (Basel). 2025-5-18

[4]
Advances in Magnetically Controlled Medical Robotics: A Review of Actuation Systems, Continuum Designs, and Clinical Prospects for Minimally Invasive Therapies.

Micromachines (Basel). 2025-5-6

[5]
Magnetic Membranes for Cell Growth Under Curved and Reversible Deformations.

Small Sci. 2024-4-30

[6]
Addressable and perceptible dynamic reprogram of ferromagnetic soft machines.

Nat Commun. 2025-3-6

[7]
Wireless, Multifunctional System-Integrated Programmable Soft Robot.

Nanomicro Lett. 2025-2-17

[8]
Electrified Dynamically Responsive Ammonia Decomposition to Hydrogen Based on Magnetic Heating of a Ru Nanocatalyst.

ChemSusChem. 2025-4-14

[9]
Heterogeneous multiple soft millirobots in three-dimensional lumens.

Sci Adv. 2024-11-8

[10]
Magnetically Driven Quadruped Soft Robot with Multimodal Motion for Targeted Drug Delivery.

Biomimetics (Basel). 2024-9-16

本文引用的文献

[1]
Remotely Guided Immunobots Engaged in Anti-Tumorigenic Phenotypes for Targeted Cancer Immunotherapy.

Small. 2022-11

[2]
Liquid Metal-Elastomer Composites with Dual-Energy Transmission Mode for Multifunctional Miniature Untethered Magnetic Robots.

Adv Sci (Weinh). 2022-11

[3]
Wireless Miniature Magnetic Phase-Change Soft Actuators.

Adv Mater. 2022-10

[4]
On-demand anchoring of wireless soft miniature robots on soft surfaces.

Proc Natl Acad Sci U S A. 2022-8-23

[5]
Miniature coiled artificial muscle for wireless soft medical devices.

Sci Adv. 2022-3-11

[6]
Recent advances in selective photothermal therapy of tumor.

J Nanobiotechnology. 2021-10-24

[7]
3D printed personalized magnetic micromachines from patient blood-derived biomaterials.

Sci Adv. 2021-9-3

[8]
A review of the osteoderms of lizards (Reptilia: Squamata).

Biol Rev Camb Philos Soc. 2022-2

[9]
Soft-bodied adaptive multimodal locomotion strategies in fluid-filled confined spaces.

Sci Adv. 2021-6-30

[10]
Wirelessly Actuated Thermo- and Magneto-Responsive Soft Bimorph Materials with Programmable Shape-Morphing.

Adv Mater. 2021-7

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索