急性中耳炎的三日和七日治疗：一项双盲抗生素试验。
Three-day and seven-day treatment in acute otitis media: a double-blind antibiotic trial.
作者信息
Jones R, Bain J
出版信息
J R Coll Gen Pract. 1986 Aug;36(289):356-8.
Abstract
Ninety-six children with acute otitis media were randomized into a double-blind general practice trial of three-day and seven-day courses of cefaclor 125 mg tds. These regimens were equally effective in terms of resolution of symptoms and signs of otitis media, even in children presenting with bulging of the tympanic membrane. There was no difference between the groups in the recurrence of middle-ear infection during the six weeks after entry to the trial. The results provide further evidence about the effectiveness of short courses of antibiotics for children with presumed middle-ear infection.
摘要
96名急性中耳炎患儿被随机分为两组，进行一项双盲全科医学试验，分别接受为期三天和七天的头孢克洛治疗，剂量为125毫克，每日三次。就中耳炎症状和体征的缓解而言，这两种治疗方案同样有效，即使是鼓膜膨出的患儿也是如此。在进入试验后的六周内，两组中耳感染复发情况没有差异。这些结果为短疗程抗生素治疗疑似中耳感染患儿的有效性提供了进一步证据。
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