Epigenetics and Stem Cell Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina.
Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Kidney360. 2023 Aug 1;4(8):1174-1180. doi: 10.34067/KID.0000000000000194. Epub 2023 Jun 26.
Vasopressin is a highly conserved peptide hormone that has been traditionally associated with water homeostasis. There is accumulating evidence in both humans and animal models that vasopressin is implicated in the regulation of metabolism. This review focuses on the effects that vasopressin exerts on the regulation of glucose and fatty acids with a particular emphasis on the potential repercussions of metabolic dysregulation in kidney disease.
加压素是一种高度保守的肽类激素，传统上与水稳态有关。越来越多的证据表明，加压素参与了代谢的调节，无论是在人类还是动物模型中都是如此。这篇综述重点介绍了加压素对葡萄糖和脂肪酸调节的影响，特别强调了代谢失调在肾脏疾病中的潜在影响。
