Saadeh Marguerita, Xia Xin, Verspoor Eline, Welmer Anna-Karin, Dekhtyar Serhiy, Vetrano Davide L, Fratiglioni Laura, Melis René J F, Calderón-Larrañaga Amaia
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet & Stockholm University, Solna, Sweden.
Department of Geriatric Medicine, Radboudumc Alzheimer Centrum, Radboud University Medical Center, Nijmegen, The Netherlands.
Innov Aging. 2023 May 4;7(5):igad040. doi: 10.1093/geroni/igad040. eCollection 2023.
Successful aging has been described as a multifactorial and dynamic process. The aims of the study were to detect aging trajectories of physical function and behavioral, psychological, and social well-being; and to explore the correlations between functional versus well-being trajectories by age group.
Data were gathered from the Swedish National Study on Aging and Care in Kungsholmen ( = 1,375). Subjects' physical function was assessed through walking speed and chair-stand tests, behavioral well-being through participation in mental and physical activities, psychological well-being through life satisfaction and positive affect, and social well-being through social connections and support. All exposures were standardized (-scores). Linear mixed models were used to estimate trajectories of physical function and well-being over a 12-year follow-up.
The steepest declines were seen for physical function (relative change [RC] in -scores across ages; RC = 3.01), followed by behavioral well-being (RC = 2.15), psychological well-being (RC = 2.01), and social well-being (RC = 0.76). Correlations between physical function and the different well-being domains were weak, especially for slopes. Stronger intercept correlations were observed among the oldest-compared to the youngest-old, especially with behavioral ( = 0.39 vs = 0.24) and psychological ( = 0.33 vs = 0.22) well-being.
Physical function declines the fastest throughout aging. The different well-being domains decline at a slower rate, which may be a possible sign of compensation against age-related functional decline, especially among the youngest-old, for whom discordances between physical function and the different well-being domains were more common.
成功老龄化被描述为一个多因素的动态过程。本研究的目的是检测身体功能以及行为、心理和社会幸福感的衰老轨迹；并按年龄组探索功能轨迹与幸福感轨迹之间的相关性。
数据来自瑞典斯德哥尔摩市的国家老龄化与护理研究（ = 1375）。通过步行速度和从椅子上站起测试评估受试者的身体功能，通过参与心理和体育活动评估行为幸福感，通过生活满意度和积极情绪评估心理幸福感，通过社会联系和支持评估社会幸福感。所有暴露因素均进行了标准化（z分数）。使用线性混合模型估计12年随访期间身体功能和幸福感的轨迹。
身体功能下降最为明显（各年龄段z分数的相对变化[RC]；RC = 3.01），其次是行为幸福感（RC = 2.15）、心理幸福感（RC = 2.01）和社会幸福感（RC = 0.76）。身体功能与不同幸福感领域之间的相关性较弱，尤其是斜率方面。与最年轻的老年人相比，最年长的老年人之间观察到更强的截距相关性，特别是与行为幸福感（ = 0.39对 = 0.24）和心理幸福感（ = 0.33对 = 0.22）。
在整个衰老过程中，身体功能下降最快。不同的幸福感领域下降速度较慢，这可能是对与年龄相关的功能下降进行补偿的一个可能迹象，特别是在最年轻的老年人中，身体功能与不同幸福感领域之间的不一致更为常见。
