Hu Yeye, He Ziliang, Zhang Wei, Niu Zhiqiang, Wang Yanting, Zhang Ji, Shen Ting, Cheng Hong, Hu Weicheng
Institute of Translational Medicine, School of Medicine, Yangzhou University, Yangzhou, 225009, China.
School of Life Sciences, Huaiyin Normal University, Huaian, 223300, China.
J Ginseng Res. 2023 Apr 8;47(5):622-6. doi: 10.1016/j.jgr.2023.04.002.
The COVID-19 pandemic has changed the world and has presented the scientific community with unprecedented challenges. Infection is associated with overproduction of proinflammatory cytokines secondary to hyperactivation of the innate immune response, inducing a cytokine storm and triggering multiorgan failure and significant morbidity/mortality. No specific treatment is yet available. For thousands of years, notoginseng has been used to treat various infectious diseases. Experimental evidence of notoginseng utility in terms of alleviating the cytokine storm, especially the cascade, and improving post-COVID-19 symptoms, suggests that notoginseng may serve as a valuable adjunct treatment for COVID-19 infection.
新冠疫情改变了世界,给科学界带来了前所未有的挑战。感染与先天免疫反应过度激活继发的促炎细胞因子过度产生有关,引发细胞因子风暴,进而导致多器官功能衰竭和高发病率/死亡率。目前尚无特效治疗方法。数千年来,三七一直被用于治疗各种传染病。三七在减轻细胞因子风暴(尤其是级联反应)以及改善新冠后症状方面的实验证据表明,三七可能是新冠感染的一种有价值的辅助治疗药物。