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肥胖、炎症、生长与代谢:对新旧肽类理解的演变及功能的不断发展

Obesity, Inflammation, Growth, and Metabolism: Evolution of Understanding and Evolving Functions of Old and New Peptides.

作者信息

Street Maria Elisabeth

机构信息

Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.

Unit of Paediatrics, University Hospital of Parma, 43126 Parma, Italy.

出版信息

J Clin Med. 2023 Jun 8;12(12):3913. doi: 10.3390/jcm12123913.

DOI:10.3390/jcm12123913
PMID:37373607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10298869/
Abstract

Obesity is a well-known low-grade chronic inflammatory disease that leads to metabolic derangements, cardiovascular complications, changes in growth, timing of puberty, bone formation, and changes in the ability to face infection [...].

摘要

肥胖是一种众所周知的低度慢性炎症性疾病,会导致代谢紊乱、心血管并发症、生长变化、青春期时间、骨骼形成以及面对感染能力的变化[...]。

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Obesity, Inflammation, Growth, and Metabolism: Evolution of Understanding and Evolving Functions of Old and New Peptides.肥胖、炎症、生长与代谢:对新旧肽类理解的演变及功能的不断发展
J Clin Med. 2023 Jun 8;12(12):3913. doi: 10.3390/jcm12123913.
2
Longitudinal associations between cardiovascular biomarkers and metabolic syndrome during puberty: the PUBMEP study.青春期心血管生物标志物与代谢综合征之间的纵向关联:PUBMEP 研究。
Eur J Pediatr. 2023 Jan;182(1):419-429. doi: 10.1007/s00431-022-04702-6. Epub 2022 Nov 15.
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[Role of chronic inflammation in adipose tissue in the pathophysiology of obesity].[慢性炎症在脂肪组织中肥胖病理生理学中的作用]
Nihon Rinsho. 2013 Feb;71(2):225-30.
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The evolving role of inflammation in obesity and the metabolic syndrome.炎症在肥胖和代谢综合征中不断演变的作用。
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Cardiovascular diseases and metabolic abnormalities associated with obesity: What is the role of inflammatory responses? A systematic review.心血管疾病与肥胖相关的代谢异常:炎症反应的作用是什么?系统综述。
Microvasc Res. 2020 Sep;131:104023. doi: 10.1016/j.mvr.2020.104023. Epub 2020 May 30.
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[Inflammatory changes in obese adipose tissue].[肥胖脂肪组织中的炎症变化]
Nihon Rinsho. 2009 Feb;67(2):270-6.
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Pancreatic steatosis: an update.胰腺脂肪变性:更新。
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Fatty acids and chronic low grade inflammation associated with obesity and the metabolic syndrome.脂肪酸与肥胖及代谢综合征相关的慢性低度炎症。
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本文引用的文献

1
Skeptical Look at the Clinical Implication of Metabolic Syndrome in Childhood Obesity.对儿童肥胖中代谢综合征临床意义的质疑审视
Children (Basel). 2023 Apr 17;10(4):735. doi: 10.3390/children10040735.
2
Clinical evaluation of patients living with obesity.肥胖患者的临床评估。
Intern Emerg Med. 2023 Aug;18(5):1273-1285. doi: 10.1007/s11739-023-03263-2. Epub 2023 Apr 29.
3
The Advanced Diabetes Technologies for Reduction of the Frequency of Hypoglycemia and Minimizing the Occurrence of Severe Hypoglycemia in Children and Adolescents with Type 1 Diabetes.用于降低1型糖尿病儿童和青少年低血糖发生频率及减少严重低血糖发生的先进糖尿病技术
J Clin Med. 2023 Jan 18;12(3):781. doi: 10.3390/jcm12030781.
4
Adipokines, Hepatokines and Myokines: Focus on Their Role and Molecular Mechanisms in Adipose Tissue Inflammation.脂联素、肝激素和肌激素:聚焦它们在脂肪组织炎症中的作用和分子机制。
Front Endocrinol (Lausanne). 2022 Jul 14;13:873699. doi: 10.3389/fendo.2022.873699. eCollection 2022.
5
Impact of CFTR Modulators on Beta-Cell Function in Children and Young Adults with Cystic Fibrosis.CFTR调节剂对患有囊性纤维化的儿童和青年β细胞功能的影响。
J Clin Med. 2022 Jul 17;11(14):4149. doi: 10.3390/jcm11144149.
6
Evaluation of Circulating Chitotriosidase Activity in Children with Obesity.肥胖儿童循环几丁质酶活性的评估
J Clin Med. 2022 Jun 23;11(13):3634. doi: 10.3390/jcm11133634.
7
Impact of Deprivation on Obesity in Children with PWS.贫困对普拉德-威利综合征患儿肥胖的影响。
J Clin Med. 2022 Apr 18;11(8):2255. doi: 10.3390/jcm11082255.
8
A Multivariate Analysis of "Metabolic Phenotype" Patterns in Children and Adolescents with Obesity for the Early Stratification of Patients at Risk of Metabolic Syndrome.对肥胖儿童和青少年的“代谢表型”模式进行多变量分析,以对代谢综合征风险患者进行早期分层。
J Clin Med. 2022 Mar 27;11(7):1856. doi: 10.3390/jcm11071856.
9
Free Insulin-like Growth Factor (IGF)-I in Children with PWS.普拉德-威利综合征患儿的游离胰岛素样生长因子(IGF)-I
J Clin Med. 2022 Feb 26;11(5):1280. doi: 10.3390/jcm11051280.
10
Inflammatory Diseases and Growth: Effects on the GH-IGF Axis and on Growth Plate.炎症性疾病与生长:对生长激素 - 胰岛素样生长因子轴及生长板的影响
Int J Mol Sci. 2017 Aug 31;18(9):1878. doi: 10.3390/ijms18091878.