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学习与记忆的神经生物学

The neurobiology of learning and memory.

作者信息

Thompson R F

出版信息

Science. 1986 Aug 29;233(4767):941-7. doi: 10.1126/science.3738519.

Abstract

Study of the neurobiology of learning and memory is in a most exciting phase. Behavioral studies in animals are characterizing the categories and properties of learning and memory; essential memory trace circuits in the brain are being defined and localized in mammalian models; work on human memory and the brain is identifying neuronal systems involved in memory; the neuronal, neurochemical, molecular, and biophysical substrates of memory are beginning to be understood in both invertebrate and vertebrate systems; and theoretical and mathematical analysis of basic associative learning and of neuronal networks in proceeding apace. Likely applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.

摘要

学习与记忆的神经生物学研究正处于一个极其令人兴奋的阶段。对动物的行为研究正在描述学习与记忆的类别和特性;大脑中基本的记忆痕迹回路正在哺乳动物模型中被界定和定位;关于人类记忆与大脑的研究正在识别参与记忆的神经元系统;在无脊椎动物和脊椎动物系统中,记忆的神经元、神经化学、分子和生物物理基础都开始被理解;并且对基本联想学习和神经元网络的理论及数学分析也在迅速推进。对学习与记忆神经基础的这一新认识可能的应用范围从教育到学习障碍的治疗,再到新人工智能系统的设计。

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