Vezon G, Piquet Y, Manier C, Schooneman F, Mesnier F, Moulinier J
Vox Sang. 1986;51 Suppl 1:40-4. doi: 10.1111/j.1423-0410.1986.tb01993.x.
Four plasmapheresis systems were comparatively studied: a centrifugation system (Haemonetics Model 50) and three filtration ones (Dideco BT 810, Organon Teknika PLASMAPUR and HemaScience Autopheresis Plasmacell). For each separator we studied the technical conditions for plasma separation, the biological characteristics of the collected plasma and the in vitro recovery of factor VIIc after preparation of cryoprecipitates. Concerning the plasma extraction rate, the HemaScience apparatus was the most efficient but values were quite similar to those obtained with the Organon Teknika machine. Contaminating cells were only found in plasma separated with the Haemonetics. Total protein and immunoglobulin levels were higher in plasma collected with the Haemonetics and HaemaScience systems. Factor VIIIc activity was comparable in plasma separated by filtration or by centrifugation while fibrinopeptide A levels were higher in plasma collected by Haemonetics. Whatever the machine, no statistical difference was observed when in vitro recovery of factor VIII was studied.
一种离心系统（Haemonetics Model 50）和三种过滤系统（Dideco BT 810、Organon Teknika PLASMAPUR和HemaScience Autopheresis Plasmacell）。对于每种分离器，我们研究了血浆分离的技术条件、所收集血浆的生物学特性以及冷沉淀制备后因子VIIc的体外回收率。关于血浆提取率，HemaScience设备效率最高，但数值与用Organon Teknika机器获得的数值非常相似。仅在用Haemonetics分离的血浆中发现了污染细胞。用Haemonetics和HemaScience系统收集的血浆中总蛋白和免疫球蛋白水平较高。通过过滤或离心分离的血浆中因子VIIIc活性相当，而用Haemonetics收集的血浆中纤维蛋白肽A水平较高。无论使用何种机器，在研究因子VIII的体外回收率时均未观察到统计学差异。
