Kristoferitsch W, Lanschützer H
Wien Klin Wochenschr. 1986 Jun 13;98(12):386-8.
Paired cerebrospinal fluid (CSF) and serum samples from 15 patients with meningopolyneuritis Garin-Bujadoux-Bannwarth (MPN-GBB) were investigated by agarosegel electrophoresis (AE) and consecutive immunofixation (IF). Oligoclonal immunoglobulin (Ig) was detected in the CSF in 13 cases, 8 of which showed oligoclonal IgM; oligoclonal Ig was not found in the respective serum samples. Local CSF synthesis of IgM is a characteristic feature in patients with MPN-GBB. Further serological testing for borreliosis is mandatory in such cases.
对15例加林-布雅杜-班沃思脑膜多神经炎（MPN-GBB）患者的配对脑脊液（CSF）和血清样本进行了琼脂糖凝胶电泳（AE）及连续免疫固定（IF）检测。13例患者的脑脊液中检测到寡克隆免疫球蛋白（Ig），其中8例显示寡克隆IgM；相应血清样本中未发现寡克隆Ig。IgM的脑脊液局部合成是MPN-GBB患者的一个特征性表现。在此类病例中，进一步进行莱姆病血清学检测是必要的。
