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[加林-布雅杜-班瓦特脑脊膜神经根炎的脑脊液变化]

[Cerebrospinal fluid changes in Garin-Bujadoux-Bannwarth meningoradiculitis].

作者信息

Maida E, Kristoferitsch W, Spiel G

出版信息

Nervenarzt. 1986 Mar;57(3):149-52.

PMID:3960231
Abstract

56 cerebrospinal fluid (CSF) and 46 matched serum samples were investigated in 23 patients, who suffered from meningopolyneuritis Garin-Bujadoux-Bannwarth. CSF cells and proteins were elevated for several months. The most prominent findings were the predominantly lymphocytic cell reactions with high numbers of plasma cells and the persistence of humoral immune reactions, i.e. intrathecally produced IgG, IgM and IgA. Both give evidence that the responsible infectious agent has rather low pathogenic but high immunogenic properties and that it has a tendency for a long persistence in the nervous system.

摘要

对23例患有加林-布雅杜-班瓦特脑膜多神经炎的患者的56份脑脊液(CSF)样本和46份配对血清样本进行了研究。脑脊液中的细胞和蛋白质在几个月内一直升高。最显著的发现是主要为淋巴细胞反应,伴有大量浆细胞,以及体液免疫反应持续存在,即鞘内产生的IgG、IgM和IgA。这两者都表明,致病感染因子致病性较低但免疫原性较高,并且有在神经系统中长期持续存在的倾向。

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