Busoni P, Andreuccetti T
Anaesth Intensive Care. 1986 May;14(2):140-4. doi: 10.1177/0310057X8601400207.
A mathematical model correlating the spread of analgesia to the dose of local anaesthetic and to age or body weight was found analysing the data of 763 caudal blocks in children from age one day to twelve years. Two graphs have been plotted: (1) spread of analgesia, dose, age and (2) spread of analgesia, dose, weight. Both age and weight can be used as predictors to determine the desired level of analgesia, but weight is more useful in very young patients while age is a better guide in older children.
通过分析763例1天至12岁儿童骶管阻滞的数据,发现了一个将镇痛范围与局部麻醉药剂量以及年龄或体重相关联的数学模型。绘制了两张图表:(1)镇痛范围、剂量、年龄;(2)镇痛范围、剂量、体重。年龄和体重都可以用作预测指标来确定所需的镇痛水平,但体重在非常年幼的患者中更有用,而年龄在较大儿童中是更好的指导指标。