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A cycloruthenated complex, ruthenium (II) Z (RuZ) overcomes and multidrug resistance in cancer cells: A pivotal breakthrough.

作者信息

Cao Luqi, Xie Yuhao, Chen Zhesheng, Ashby Charles R

机构信息

Institute for Biotechnology, St. John's University, Queens, New York 11439, USA.

Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, USA.

出版信息

J Transl Int Med. 2023 Jul 5;11(2):95-97. doi: 10.2478/jtim-2023-0081. eCollection 2023 Jul.

DOI:10.2478/jtim-2023-0081
PMID:37408573
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10318915/
Abstract
摘要

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本文引用的文献

1
Cycloruthenated Self-Assembly with Metabolic Inhibition to Efficiently Overcome Multidrug Resistance in Cancers.环钌自组装与代谢抑制协同作用，高效克服癌症多药耐药性。
Adv Mater. 2022 Jan;34(1):e2100245. doi: 10.1002/adma.202100245. Epub 2021 Oct 24.
2
A view on drug resistance in cancer.癌症耐药性的观点。
Nature. 2019 Nov;575(7782):299-309. doi: 10.1038/s41586-019-1730-1. Epub 2019 Nov 13.
3
Apoptosis-independent organoruthenium anticancer complexes that overcome multidrug resistance: self-assembly and phenotypic screening strategies.克服多药耐药性的非凋亡依赖性有机钌抗癌复合物：自组装和表型筛选策略
Chem Sci. 2017 May 1;8(5):3641-3649. doi: 10.1039/c7sc00497d. Epub 2017 Feb 28.
4
Structure of the human multidrug transporter ABCG2.人源多药耐药相关蛋白 ABCG2 的结构。
Nature. 2017 Jun 22;546(7659):504-509. doi: 10.1038/nature22345. Epub 2017 May 29.
5
Doxorubicin pathways: pharmacodynamics and adverse effects.多柔比星作用途径：药效学与不良反应
Pharmacogenet Genomics. 2011 Jul;21(7):440-6. doi: 10.1097/FPC.0b013e32833ffb56.
6
Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes.通过单步阿霉素筛选的癌细胞通过表观遗传变化过度表达ABCG2药物转运蛋白。
Br J Cancer. 2008 May 6;98(9):1515-24. doi: 10.1038/sj.bjc.6604334. Epub 2008 Apr 1.