Kasallis Summer, Bru Jean-Louis, Chang Rendell, Zhuo Quantum, Siryaporn Albert
Department of Physics & Astronomy, University of California Irvine, Irvine, CA 92697, USA.
Department of Molecular Biology & Biochemistry, University of California Irvine, Irvine, CA 92697, USA.
Curr Opin Solid State Mater Sci. 2023 Jun;27(3). doi: 10.1016/j.cossms.2023.101080. Epub 2023 Apr 29.
Swarming is a collective bacterial behavior in which a dense population of bacterial cells moves over a porous surface, resulting in the expansion of the population. This collective behavior can guide bacteria away from potential stressors such as antibiotics and bacterial viruses. However, the mechanisms responsible for the organization of swarms are not understood. Here, we briefly review models that are based on bacterial sensing and fluid mechanics that are proposed to guide swarming in the pathogenic bacterium . To provide further insight into the role of fluid mechanics in swarms, we track the movement of tendrils and the flow of surfactant using a novel technique that we have developed, Imaging of Reflected Illuminated Structures (IRIS). Our measurements show that tendrils and surfactants form distinct layers that grow in lockstep with each other. The results raise new questions about existing swarming models and the possibility that the flow of surfactants impacts tendril development. These findings emphasize that swarm organization involves an interplay between biological processes and fluid mechanics.
群体运动是一种细菌的集体行为，在这种行为中，高密度的细菌细胞群体在多孔表面移动，导致群体扩张。这种集体行为可以引导细菌远离潜在的应激源，如抗生素和噬菌体。然而，负责群体组织的机制尚不清楚。在这里，我们简要回顾基于细菌感知和流体力学的模型，这些模型被认为可以指导病原菌的群体运动。为了进一步深入了解流体力学在群体运动中的作用，我们使用我们开发的一种新技术——反射照明结构成像（IRIS）来追踪卷须的运动和表面活性剂的流动。我们的测量结果表明，卷须和表面活性剂形成了相互同步生长的不同层。这些结果对现有的群体运动模型以及表面活性剂流动影响卷须发育的可能性提出了新的问题。这些发现强调群体组织涉及生物过程和流体力学之间的相互作用。
