Guangdong Provincial Key Laboratory for Plant Epigenetics, Longhua Bioindustry and Innovation Research Institute, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
Int J Mol Sci. 2023 Jul 4;24(13):11081. doi: 10.3390/ijms241311081.
Understanding the mechanisms of responses to high temperatures in Arabidopsis will provide insights into how plants may mitigate heat stress under global climate change. And exploring the interconnections of different modification levels in heat stress response could help us to understand the molecular mechanism of heat stress response in Arabidopsis more comprehensively and precisely. In this paper, we combined multiomics analyses to explore the common heat stress-responsive genes and specific heat-responsive metabolic pathways in Arabidopsis leaf, seedling, and seed tissues. We found that genes such as play a role in promoting proper protein folding in response to HS (Heat stress). In addition, it was revealed that the binding profile of is altered under elevated temperature conditions. Finally, we also show that two microRNAs, ath-mir156h and ath-mir166b-5p, may be core regulatory molecules in HS. Also elucidated that under HS, plants can regulate specific regulatory mechanisms, such as oxygen levels, by altering the degree of CHH methylation.
理解拟南芥对高温响应的机制将为了解植物在全球气候变化下如何减轻热应激提供线索。探索热应激响应中不同修饰水平的相互联系，可以帮助我们更全面、更准确地理解拟南芥热应激响应的分子机制。在本文中，我们结合多组学分析，探讨了拟南芥叶、幼苗和种子组织中常见的热应激响应基因和特定的热响应代谢途径。我们发现， 等基因在应对 HS（热应激）时发挥作用，促进适当的蛋白质折叠。此外，还揭示了 在高温条件下结合谱发生改变。最后，我们还表明，两个 microRNAs，ath-mir156h 和 ath-mir166b-5p，可能是 HS 的核心调节分子。此外还阐明，在 HS 下，植物可以通过改变 CHH 甲基化程度来调节特定的调节机制，如氧水平。
