Cognitive Circuitry Laboratory (CoCiLa), School of Biological Sciences, Seoul National University, Seoul 08826, Korea.
Mol Cells. 2023 Aug 31;46(8):461-469. doi: 10.14348/molcells.2023.0051. Epub 2023 Jul 17.
The tail of the striatum (TS) is located at the caudal end in the striatum. Recent studies have advanced our knowledge of the anatomy and function of the TS but also raised questions about the differences between rodent and primate TS. In this review, we compare the anatomy and function of the TS in rodent and primate brains. The primate TS is expanded more caudally during brain development in comparison with the rodent TS. Additionally, five sensory inputs from the cortex and thalamus converge in the rodent TS, but this convergence is not observed in the primate TS. The primate TS, including the caudate tail and putamen tail, primarily receives inputs from the visual areas, implying a specialized function in processing visual inputs for action generation. This anatomical difference leads to further discussion of cellular circuit models to comprehend how the primate brain processes a wider range of complex visual stimuli to produce habitual behavior as compared with the rodent brain. Examining these differences and considering possible neural models may provide better understanding of the anatomy and function of the primate TS.
纹状体尾部（TS）位于纹状体的尾端。最近的研究不仅增进了我们对 TS 的解剖和功能的了解，还提出了关于啮齿动物和灵长类动物 TS 之间差异的问题。在这篇综述中，我们比较了啮齿动物和灵长类动物大脑中 TS 的解剖和功能。与啮齿动物 TS 相比，灵长类动物 TS 在大脑发育过程中向尾部扩展得更多。此外，来自大脑皮层和丘脑的五个感觉输入在啮齿动物 TS 中汇聚，但在灵长类动物 TS 中则没有观察到这种汇聚。包括尾状核和壳核在内的灵长类动物 TS，主要接收来自视觉区域的输入，这意味着其在处理用于产生动作的视觉输入方面具有特殊功能。这种解剖学差异导致进一步讨论细胞回路模型，以理解与啮齿动物大脑相比，灵长类动物大脑如何处理更广泛的复杂视觉刺激，从而产生习惯性行为。研究这些差异并考虑可能的神经模型，可能有助于更好地理解灵长类动物 TS 的解剖和功能。
