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一个高分辨率的大规模病理性和正常白细胞数据集。

A high-resolution large-scale dataset of pathological and normal white blood cells.

机构信息

Department of Cybernetics and Biomedical Engineering, Faculty of Electrical Engineering and Computer Science, VSB-Technical University of Ostrava, Ostrava, Czech Republic.

出版信息

Sci Data. 2023 Jul 19;10(1):466. doi: 10.1038/s41597-023-02378-7.

Abstract

Microscopic examination plays a significant role in the initial screening for a variety of hematological, as well as non-hematological, diagnoses. Microscopic blood smear examination that is considered a key diagnostic technique, is in recent clinical practice still performed manually, which is not only time consuming, but can lead to human errors. Although automated and semi-automated systems have been developed in recent years, their high purchasing and maintenance costs make them unaffordable for many medical institutions. Even though much research has been conducted lately to explore more accurate and feasible solutions, most researchers had to deal with a lack of medical data. To address the lack of large-scale databases in this field, we created a high-resolution dataset containing a total of 16027 annotated white blood cells. Moreover, the dataset covers overall 9 types of white blood cells, including clinically significant pathological findings. Since we used high-quality acquisition equipment, the dataset provides one of the highest quality images of blood cells, achieving an approximate resolution of 42 pixels per 1 μm.

摘要

显微镜检查在各种血液学和非血液学诊断的初步筛查中起着重要作用。显微镜血涂片检查被认为是一种关键的诊断技术,但在最近的临床实践中仍然是手动进行的,这不仅耗时,而且容易导致人为错误。尽管近年来已经开发出自动化和半自动化系统,但它们的高购买和维护成本使得许多医疗机构无法承受。尽管最近进行了大量研究来探索更准确和可行的解决方案,但大多数研究人员不得不应对缺乏医疗数据的问题。为了解决该领域缺乏大规模数据库的问题,我们创建了一个包含总共 16027 个注释白细胞的高分辨率数据集。此外,该数据集涵盖了 9 种类型的白细胞,包括临床上有意义的病理发现。由于我们使用了高质量的采集设备,该数据集提供了血细胞的最高质量图像之一,其分辨率约为每 1μm 42 像素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8526/10356748/0a66739f29e4/41597_2023_2378_Fig1_HTML.jpg

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