Çakmak Aslıhan, Şimşek Senem, İnal İnce Deniz, Sağlam Melda, Çalık Kütükcü Ebru, Vardar Yağlı Naciye, Karaya Gül
Hacettepe University Faculty of Physical Therapy and Rehabilitation, Ankara, Turkey.
Division of Allergy and Clinical Immunology, Department of Chest Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Thorac Res Pract. 2023 Jul;24(4):194-201. doi: 10.5152/ThoracResPract.2023.22198.
The Nijmegen Questionnaire (NQ) enables the assessment and identification of symptoms related to respiratory dysfunction and hyperventilation syndrome. The aim was to investigate the validity of the Turkish version of the NQ in asthmatics.
Fifty-four individuals with asthma were included. Spirometry was performed. Dyspnea was assessed using the modified Borg and modified Medical Research Council scales. Breath-holding time was recorded. End-tidal carbon dioxide was measured using a portable capnograph. Oxygen saturation and heart rate were recorded. Asthma Control Test was used to evaluate the asthma control level. Quality of life was assessed using the Asthma Quality of Life Questionnaire and Nottingham Health Profile. Beck Depression Inventory was used to determine depression.
Bartlett's test of sphericity (360.749, df 105, P < .001) and Kaiser-Meyer-Olkin criterion (0.752) for 15-item NQ supported a single-factor model with 36.38% of explained variability through principal component analysis and explanatory factor analysis. For 15-item NQ with this single-factor model, Cronbach's alpha was 0.872, and the test-retest reliability was 0.628. There was a significant negative correlation between NQ and Asthma Control Test (r = -0.448), and Asthma Quality of Life Questionnaire (r = -0.743) and a significant positive association with Beck Depression Inventory (r = 0.477), Nottingham Health Profile-energy (r = 0.370), Nottingham Health Profile-pain (r = 0.313), Nottingham Health Profile-sleep (r = 0.294), and Nottingham Health Profile-physical activity scores (r = 0.406) (P < .05).
The 15-item Turkish version of the NQ is valid and reliable in asthmatics. Individuals with uncontrolled asthma have higher NQ scores than those with well-controlled asthma. NQ is associated with asthma control level, asthma-related quality of life, health profile, and depression.
奈梅亨问卷（NQ）可用于评估和识别与呼吸功能障碍及过度通气综合征相关的症状。本研究旨在探讨NQ土耳其语版本在哮喘患者中的有效性。
纳入54例哮喘患者。进行肺功能测定。使用改良的博格量表和改良的医学研究委员会量表评估呼吸困难程度。记录屏气时间。使用便携式二氧化碳监测仪测量呼气末二氧化碳。记录血氧饱和度和心率。使用哮喘控制测试评估哮喘控制水平。使用哮喘生活质量问卷和诺丁汉健康量表评估生活质量。使用贝克抑郁量表确定抑郁情况。
针对15项NQ的巴特利特球形检验（360.749，自由度105，P <.001）和凯泽-迈耶-奥尔金标准（0.752）通过主成分分析和解释性因子分析支持单因素模型，解释变异率为36.38%。对于具有此单因素模型的15项NQ，克朗巴赫α系数为0.872，重测信度为0.628。NQ与哮喘控制测试（r = -0.448）、哮喘生活质量问卷（r = -0.743）之间存在显著负相关，与贝克抑郁量表（r = 0.477）、诺丁汉健康量表-精力（r = 0.370）、诺丁汉健康量表-疼痛（r = 0.313）、诺丁汉健康量表-睡眠（r = 0.294）以及诺丁汉健康量表-身体活动得分（r = 0.406）之间存在显著正相关（P <.05）。
15项NQ土耳其语版本在哮喘患者中有效且可靠。哮喘控制不佳的患者NQ得分高于控制良好的患者。NQ与哮喘控制水平、哮喘相关生活质量健康量表及抑郁相关。
